U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MMP28 matrix metallopeptidase 28 [ Gallus gallus (chicken) ]

Gene ID: 417523, updated on 5-Mar-2024

Summary

Symbol
MMP28provided by CGNC
Full Name
matrix metallopeptidase 28provided by CGNC
Primary source
CGNC:1477
See related
Ensembl:ENSGALG00010029622
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: 19
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 19 NC_052550.1 (4854675..4864531)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 19 NC_052591.1 (4583056..4592942)

Chromosome 19 - NC_052550.1Genomic Context describing neighboring genes Neighboring gene cytochrome p450 oxidoreductase Neighboring gene rhomboid domain containing 2 Neighboring gene TATA-box binding protein associated factor 15 Neighboring gene growth arrest specific 2 like 2 Neighboring gene RAS like family 10 member B Neighboring gene adaptor related protein complex 2 beta 1 subunit Neighboring gene peroxisomal biogenesis factor 12

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in collagen catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
matrix metalloproteinase-28

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052550.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4854675..4864531
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_415771.7XP_415771.6  matrix metalloproteinase-28 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AN12
    Related
    ENSGALP00010044314.1, ENSGALT00010071624.1
    Conserved Domains (2) summary
    cd00094
    Location:309476
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:111265
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052591.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4583056..4592942
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040687143.2XP_040543077.1  matrix metalloproteinase-28 isoform X1

    Conserved Domains (3) summary
    cd00094
    Location:306473
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:108262
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam01471
    Location:2680
    PG_binding_1; Putative peptidoglycan binding domain
  2. XM_040687144.2XP_040543078.1  matrix metalloproteinase-28 isoform X2

    Conserved Domains (3) summary
    cd00094
    Location:224391
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    pfam01471
    Location:2680
    PG_binding_1; Putative peptidoglycan binding domain
    cl00064
    Location:108180
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...