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PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha [ Gallus gallus (chicken) ]

Gene ID: 417438, updated on 3-Apr-2024

Summary

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Symbol
PRKAR1Aprovided by CGNC
Full Name
protein kinase cAMP-dependent type I regulatory subunit alphaprovided by CGNC
Primary source
CGNC:3113
See related
Ensembl:ENSGALG00010029399
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 18 NC_052549.1 (8487580..8503807)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 18 NC_052590.1 (8081606..8097810)

Chromosome 18 - NC_052549.1Genomic Context describing neighboring genes Neighboring gene arylsulfatase G Neighboring gene solute carrier family 16 member 6 Neighboring gene WD repeat domain, phosphoinositide interacting 1 Neighboring gene uncharacterized LOC107052244 Neighboring gene FAM20A, golgi associated secretory pathway pseudokinase Neighboring gene ATP binding cassette subfamily A member 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Aggregates of cAMP-dependent kinase isoforms characterize different areas in the developing central nervous system of the chicken, Gallus gallus. Mucignat-Caretta C, et al. Dev Neurosci, 2011. PMID 21876332
  2. Manipulations of PKA in chick limb development reveal roles in digit patterning including a positive role in Sonic Hedgehog signaling. Tiecke E, et al. Dev Biol, 2007 May 1. PMID 17376427
  3. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. In chicken brain PKA RI aggregates were detected first in the olfactory bulb, around embryonic day 14; within 3 days they appeared in the hyperpallium and nidopallium, where the most intense labeling was observed in the perihatching period
    Title: Aggregates of cAMP-dependent kinase isoforms characterize different areas in the developing central nervous system of the chicken, Gallus gallus.
  2. Manipulations of PKA in chick limb development reveal roles in digit patterning including a positive role in Sonic Hedgehog signaling.
    Title: Manipulations of PKA in chick limb development reveal roles in digit patterning including a positive role in Sonic Hedgehog signaling.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cAMP-dependent protein kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of cAMP-dependent protein kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cAMP-dependent protein kinase type I-alpha regulatory subunit
Names
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
NP_001007846.1
XP_015135378.1
XP_015135380.1
XP_040505438.1
XP_046757999.1
XP_046785390.1
XP_046785391.1
XP_046785392.1
XP_046785393.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007845.2 → NP_001007846.1  cAMP-dependent protein kinase type I-alpha regulatory subunit

    See identical proteins and their annotated locations for NP_001007846.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000317
    UniProtKB/Swiss-Prot
    Q5ZM91
    UniProtKB/TrEMBL
    A0A8V1ACT0
    Conserved Domains (2) summary
    cd12101
    Location:18 → 63
    DD_RIalpha_PKA; Dimerization/Docking domain of the Type I alpha Regulatory subunit of cAMP-dependent protein kinase
    cd00038
    Location:138 → 247
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052549.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    8487580..8503807
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040649504.2 → XP_040505438.1  cAMP-dependent protein kinase type I-alpha regulatory subunit isoform X1

    UniProtKB/Swiss-Prot
    Q5ZM91
    UniProtKB/TrEMBL
    A0A8V1ACT0
    Conserved Domains (2) summary
    cd12101
    Location:18 → 63
    DD_RIalpha_PKA; Dimerization/Docking domain of the Type I alpha Regulatory subunit of cAMP-dependent protein kinase
    cd00038
    Location:138 → 247
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

  2. XM_015279892.4 → XP_015135378.1  cAMP-dependent protein kinase type I-alpha regulatory subunit isoform X1

    UniProtKB/Swiss-Prot
    Q5ZM91
    UniProtKB/TrEMBL
    A0A8V1ACT0
    Related
    ENSGALP00010043800.1, ENSGALT00010071109.1
    Conserved Domains (2) summary
    cd12101
    Location:18 → 63
    DD_RIalpha_PKA; Dimerization/Docking domain of the Type I alpha Regulatory subunit of cAMP-dependent protein kinase
    cd00038
    Location:138 → 247
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

  3. XM_046902043.1 → XP_046757999.1  cAMP-dependent protein kinase type I-alpha regulatory subunit isoform X1

    UniProtKB/Swiss-Prot
    Q5ZM91

  4. XM_015279894.4 → XP_015135380.1  cAMP-dependent protein kinase type I-alpha regulatory subunit isoform X1

    UniProtKB/Swiss-Prot
    Q5ZM91
    UniProtKB/TrEMBL
    A0A8V1ACT0
    Conserved Domains (2) summary
    cd12101
    Location:18 → 63
    DD_RIalpha_PKA; Dimerization/Docking domain of the Type I alpha Regulatory subunit of cAMP-dependent protein kinase
    cd00038
    Location:138 → 247
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052590.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    8081606..8097810
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046929434.1 → XP_046785390.1  cAMP-dependent protein kinase type I-alpha regulatory subunit isoform X1

    UniProtKB/Swiss-Prot
    Q5ZM91

  2. XM_046929435.1 → XP_046785391.1  cAMP-dependent protein kinase type I-alpha regulatory subunit isoform X1

    UniProtKB/Swiss-Prot
    Q5ZM91

  3. XM_046929437.1 → XP_046785393.1  cAMP-dependent protein kinase type I-alpha regulatory subunit isoform X1

    UniProtKB/Swiss-Prot
    Q5ZM91

  4. XM_046929436.1 → XP_046785392.1  cAMP-dependent protein kinase type I-alpha regulatory subunit isoform X1

    UniProtKB/Swiss-Prot
    Q5ZM91
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5ZM91.1 GenPept UniProtKB/Swiss-Prot:Q5ZM91

Gene LinkOut

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