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MAP2K4 mitogen-activated protein kinase kinase 4 [ Gallus gallus (chicken) ]

Gene ID: 417312, updated on 5-Mar-2024

Summary

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Symbol
MAP2K4provided by CGNC
Full Name
mitogen-activated protein kinase kinase 4provided by CGNC
Primary source
CGNC:668
See related
Ensembl:ENSGALG00010029573
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
15
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 18 NC_052549.1 (1330629..1419212)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 18 NC_052590.1 (899225..988239)

Chromosome 18 - NC_052549.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 220 Neighboring gene synthesis of cytochrome C oxidase 1 Neighboring gene ADP-ribose/CDP-alcohol diphosphatase, manganese dependent Neighboring gene microRNA 1748 Neighboring gene myocardin Neighboring gene elaC ribonuclease Z 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables JUN kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity mitogen-activated protein kinase kinase 4
XP_015150723.1
XP_015150724.1
XP_015150725.1
XP_015150726.1
XP_040505548.1
XP_040505549.1
XP_040505550.1
XP_040505551.1
XP_040542852.1
XP_040542853.1
XP_040542854.1
XP_040542856.1
XP_040542857.1
XP_040542858.1
XP_040542859.1
XP_040542860.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052549.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1330629..1419212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040649617.2 → XP_040505551.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X8

    UniProtKB/TrEMBL
    A0A8V1AP85
    Related
    ENSGALP00010044163.1, ENSGALT00010071473.1
    Conserved Domains (1) summary
    cd06616
    Location:65 → 355
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  2. XM_040649615.1 → XP_040505549.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X5

    UniProtKB/TrEMBL
    A0A8V1ADR3
    Related
    ENSGALP00010044162.1, ENSGALT00010071472.1
    Conserved Domains (1) summary
    cd06616
    Location:97 → 387
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  3. XM_040649614.2 → XP_040505548.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AJ52
    Conserved Domains (1) summary
    cd06616
    Location:112 → 402
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  4. XM_040649616.2 → XP_040505550.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X7

    UniProtKB/TrEMBL
    A0A8V1AJ52
    Conserved Domains (1) summary
    cd06616
    Location:80 → 370
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  5. XM_015295237.4 → XP_015150723.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V1ADR3
    Conserved Domains (1) summary
    cd06616
    Location:133 → 423
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  6. XM_015295239.4 → XP_015150725.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X4

    UniProtKB/TrEMBL
    A0A8V1AP85, A0A8V1AP90
    Related
    ENSGALP00010044168.1, ENSGALT00010071478.1
    Conserved Domains (1) summary
    cd06616
    Location:101 → 391
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  7. XM_015295238.4 → XP_015150724.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X2

    UniProtKB/TrEMBL
    A0A1D5NVP0, A0A8V1ADR3
    Related
    ENSGALP00010044169.1, ENSGALT00010071479.1
    Conserved Domains (1) summary
    cd06616
    Location:122 → 412
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  8. XM_015295240.4 → XP_015150726.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X6

    UniProtKB/TrEMBL
    A0A8V1AP85
    Conserved Domains (1) summary
    cd06616
    Location:90 → 380
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052590.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    899225..988239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040686926.2 → XP_040542860.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X8

    UniProtKB/TrEMBL
    A0A8V1AP85
    Conserved Domains (1) summary
    cd06616
    Location:65 → 355
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  2. XM_040686923.1 → XP_040542857.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X5

    UniProtKB/TrEMBL
    A0A8V1ADR3
    Conserved Domains (1) summary
    cd06616
    Location:97 → 387
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  3. XM_040686920.2 → XP_040542854.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AJ52
    Conserved Domains (1) summary
    cd06616
    Location:112 → 402
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  4. XM_040686925.2 → XP_040542859.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X7

    UniProtKB/TrEMBL
    A0A8V1AJ52
    Conserved Domains (1) summary
    cd06616
    Location:80 → 370
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  5. XM_040686918.2 → XP_040542852.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V1ADR3
    Conserved Domains (1) summary
    cd06616
    Location:133 → 423
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  6. XM_040686922.2 → XP_040542856.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X4

    UniProtKB/TrEMBL
    A0A8V1AP85, A0A8V1AP90
    Conserved Domains (1) summary
    cd06616
    Location:101 → 391
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  7. XM_040686919.2 → XP_040542853.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X2

    UniProtKB/TrEMBL
    A0A1D5NVP0, A0A8V1ADR3
    Conserved Domains (1) summary
    cd06616
    Location:122 → 412
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

  8. XM_040686924.2 → XP_040542858.1  dual specificity mitogen-activated protein kinase kinase 4 isoform X6

    UniProtKB/TrEMBL
    A0A8V1AP85
    Conserved Domains (1) summary
    cd06616
    Location:90 → 380
    PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4
Nucleotide Protein
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