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SH2D3C SH2 domain containing 3C [ Gallus gallus (chicken) ]

Gene ID: 417225, updated on 5-Mar-2024

Summary

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Official Symbol
SH2D3Cprovided by CGNC
Official Full Name
SH2 domain containing 3Cprovided by CGNC
Primary source
CGNC:3743
See related
Ensembl:ENSGALG00010029143
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
14
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 17 NC_052548.1 (5579759..5599547)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 17 NC_052589.1 (4993447..5013265)

Chromosome 17 - NC_052548.1Genomic Context describing neighboring genes Neighboring gene endoglin Neighboring gene folylpolyglutamate synthase Neighboring gene cyclin dependent kinase 9 Neighboring gene torsin family 2 member A Neighboring gene tetratricopeptide repeat domain 16 Neighboring gene cerebral endothelial cell adhesion molecule

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SH2 domain-containing protein 3C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    5579759..5599547
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_415508.8 → XP_415508.5  SH2 domain-containing protein 3C isoform X1

    UniProtKB/TrEMBL
    A0A8V1AM75
    Related
    ENSGALP00010043115.1, ENSGALT00010070424.1
    Conserved Domains (2) summary
    cd10337
    Location:266 → 398
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:646 → 866
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  2. XM_004945815.5 → XP_004945872.3  SH2 domain-containing protein 3C isoform X3

    UniProtKB/TrEMBL
    A0A8V1AKG0
    Related
    ENSGALP00010043114.1, ENSGALT00010070423.1
    Conserved Domains (2) summary
    cd10337
    Location:56 → 188
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:436 → 656
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  3. XM_015279707.4 → XP_015135193.2  SH2 domain-containing protein 3C isoform X2

    UniProtKB/TrEMBL
    A0A8V1AIA2, A0A8V1AKG0
    Related
    ENSGALP00010043113.1, ENSGALT00010070422.1
    Conserved Domains (2) summary
    cd10337
    Location:55 → 187
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:435 → 655
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4993447..5013265
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040685839.2 → XP_040541773.1  SH2 domain-containing protein 3C isoform X1

    Conserved Domains (2) summary
    cd10337
    Location:266 → 398
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:649 → 869
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  2. XM_040685840.2 → XP_040541774.1  SH2 domain-containing protein 3C isoform X4

    UniProtKB/TrEMBL
    A0A8V1AAV9
    Conserved Domains (2) summary
    cd10337
    Location:140 → 272
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:523 → 743
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  3. XM_040685841.2 → XP_040541775.1  SH2 domain-containing protein 3C isoform X2

    UniProtKB/TrEMBL
    A0A8V1AKG0
    Conserved Domains (2) summary
    cd10337
    Location:55 → 187
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:438 → 658
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
Nucleotide Protein
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