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ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase [ Gallus gallus (chicken) ]

Gene ID: 417181, updated on 5-Mar-2024

Summary

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Symbol
ABL1provided by CGNC
Full Name
ABL proto-oncogene 1, non-receptor tyrosine kinaseprovided by CGNC
Primary source
CGNC:2837
See related
Ensembl:ENSGALG00010027607
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
ABL
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 17 NC_052548.1 (6577970..6643384)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 17 NC_052589.1 (5989050..6054623)

Chromosome 17 - NC_052548.1Genomic Context describing neighboring genes Neighboring gene microRNA 1753-1 Neighboring gene PR/SET domain 12 Neighboring gene uncharacterized LOC121107103 Neighboring gene exosome component 2 Neighboring gene pyroglutamylated RFamide peptide Neighboring gene ficolin 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cables links Robo-bound Abl kinase to N-cadherin-bound beta-catenin to mediate Slit-induced modulation of adhesion and transcription. Rhee J, et al. Nat Cell Biol, 2007 Aug. PMID 17618275

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase ABL1
Names
c-abl oncogene 1, non-receptor tyrosine kinase
c-abl oncogene 1, receptor tyrosine kinase
v-abl Abelson murine leukemia viral oncogene homolog 1
XP_015135220.3
XP_040505297.1
XP_040541912.1
XP_040541913.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    6577970..6643384
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015279734.4 → XP_015135220.3  tyrosine-protein kinase ABL1 isoform X1

    UniProtKB/TrEMBL
    A0A8V1A9P3, A0A8V1ACF7
    Related
    ENSGALP00010040916.1, ENSGALT00010066884.1
    Conserved Domains (4) summary
    smart00808
    Location:1020 → 1144
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:142 → 235
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:84 → 137
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:254 → 516
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase

  2. XM_040649363.2 → XP_040505297.1  tyrosine-protein kinase ABL1 isoform X2

    UniProtKB/TrEMBL
    A0A8V1A9P3
    Related
    ENSGALP00010040914.1, ENSGALT00010066881.1
    Conserved Domains (4) summary
    smart00808
    Location:1003 → 1127
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:125 → 218
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:67 → 120
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:237 → 499
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    5989050..6054623
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040685978.2 → XP_040541912.1  tyrosine-protein kinase ABL1 isoform X1

    UniProtKB/TrEMBL
    A0A8V1A9P3
    Conserved Domains (4) summary
    smart00808
    Location:1020 → 1144
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:142 → 235
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:84 → 137
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:254 → 516
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase

  2. XM_040685979.2 → XP_040541913.1  tyrosine-protein kinase ABL1 isoform X2

    UniProtKB/TrEMBL
    A0A8V1A9P3
    Conserved Domains (4) summary
    smart00808
    Location:1003 → 1127
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:125 → 218
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:67 → 120
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:237 → 499
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
Nucleotide Protein
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