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RAPGEF1 Rap guanine nucleotide exchange factor 1 [ Gallus gallus (chicken) ]

Gene ID: 417173, updated on 3-Apr-2024

Summary

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Symbol
RAPGEF1provided by CGNC
Full Name
Rap guanine nucleotide exchange factor 1provided by CGNC
Primary source
CGNC:2714
See related
Ensembl:ENSGALG00010028270
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
31
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 17 NC_052548.1 (6846234..6924056, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 17 NC_052589.1 (6257590..6335445, complement)

Chromosome 17 - NC_052548.1Genomic Context describing neighboring genes Neighboring gene proline rich transmembrane protein 1B Neighboring gene uridine-cytidine kinase 1 Neighboring gene mediator complex subunit 27 Neighboring gene uncharacterized LOC101751924 Neighboring gene netrin G2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rap guanine nucleotide exchange factor 1
Names
Rap guanine nucleotide exchange factor (GEF) 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    6846234..6924056 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015279741.4 → XP_015135227.2  rap guanine nucleotide exchange factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AK14
    Conserved Domains (2) summary
    smart00147
    Location:1082 → 1311
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
    smart00229
    Location:934 → 1075
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif

  2. XM_015279743.4 → XP_015135229.2  rap guanine nucleotide exchange factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V1AK14
    Conserved Domains (2) summary
    smart00147
    Location:1080 → 1309
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
    smart00229
    Location:932 → 1073
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif

  3. XM_046901868.1 → XP_046757824.1  rap guanine nucleotide exchange factor 1 isoform X3

  4. XM_046901869.1 → XP_046757825.1  rap guanine nucleotide exchange factor 1 isoform X3

    Related
    ENSGALP00010042153.1, ENSGALT00010068533.1

  5. XM_046901870.1 → XP_046757826.1  rap guanine nucleotide exchange factor 1 isoform X3

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    6257590..6335445 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040686009.2 → XP_040541943.1  rap guanine nucleotide exchange factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AK14
    Conserved Domains (2) summary
    smart00147
    Location:1082 → 1311
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
    smart00229
    Location:934 → 1075
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif

  2. XM_040686012.2 → XP_040541946.1  rap guanine nucleotide exchange factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V1AK14
    Conserved Domains (2) summary
    smart00147
    Location:1080 → 1309
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
    smart00229
    Location:932 → 1073
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif

  3. XM_046929053.1 → XP_046785009.1  rap guanine nucleotide exchange factor 1 isoform X3

  4. XM_046929054.1 → XP_046785010.1  rap guanine nucleotide exchange factor 1 isoform X3

  5. XM_046929055.1 → XP_046785011.1  rap guanine nucleotide exchange factor 1 isoform X3

Nucleotide Protein Strain
Heading Accession and Version

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