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FBXW2 F-box and WD repeat domain containing 2 [ Gallus gallus (chicken) ]

Gene ID: 417088, updated on 3-Apr-2024

Summary

Symbol
FBXW2provided by CGNC
Full Name
F-box and WD repeat domain containing 2provided by CGNC
Primary source
CGNC:566
See related
Ensembl:ENSGALG00010028712
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
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Genomic context

Location:
chromosome: 17
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 17 NC_052548.1 (10982385..10991565, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 17 NC_052589.1 (10392977..10402158, complement)

Chromosome 17 - NC_052548.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 34 Neighboring gene Ral GEF with PH domain and SH3 binding motif 1 Neighboring gene angiopoietin-like 2 Neighboring gene solute carrier family 2 member 8 Neighboring gene GTPase activating Rap/RanGAP domain like 3

Genomic regions, transcripts, and products

Pathways from PubChem

General protein information

Preferred Names
F-box/WD repeat-containing protein 2
Names
F-box and WD-40 domain protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007842.2NP_001007843.1  F-box/WD repeat-containing protein 2

    See identical proteins and their annotated locations for NP_001007843.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000308
    UniProtKB/TrEMBL
    A0A8V1AHI3, Q5ZK75
    Related
    ENSGALP00010042791.1, ENSGALT00010069512.1
    Conserved Domains (4) summary
    smart00256
    Location:6094
    FBOX; A Receptor for Ubiquitination Targets
    COG2319
    Location:133425
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:151185
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:140398
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    10982385..10991565 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015279383.4XP_015134869.1  F-box/WD repeat-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AHI3, Q5ZK75
    Related
    ENSGALP00010042789.1, ENSGALT00010069510.1
    Conserved Domains (4) summary
    smart00256
    Location:6094
    FBOX; A Receptor for Ubiquitination Targets
    COG2319
    Location:133425
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:151185
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:140398
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_046901699.1XP_046757655.1  F-box/WD repeat-containing protein 2 isoform X9

  3. XM_046901696.1XP_046757652.1  F-box/WD repeat-containing protein 2 isoform X7

  4. XM_046901697.1XP_046757653.1  F-box/WD repeat-containing protein 2 isoform X8

  5. XM_015279382.4XP_015134868.1  F-box/WD repeat-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8V1AHI3, Q5ZK75
    Conserved Domains (4) summary
    smart00256
    Location:6094
    FBOX; A Receptor for Ubiquitination Targets
    COG2319
    Location:133425
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:151185
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:140398
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  6. XM_046901694.1XP_046757650.1  F-box/WD repeat-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1A9Z5
    Related
    ENSGALP00010042787.1, ENSGALT00010069505.1
  7. XM_015279381.4XP_015134867.1  F-box/WD repeat-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V1AHI3
    Conserved Domains (4) summary
    smart00256
    Location:86120
    FBOX; A Receptor for Ubiquitination Targets
    COG2319
    Location:159438
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:177211
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:166411
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  8. XM_015279384.4XP_015134870.1  F-box/WD repeat-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8V1AFA0
    Conserved Domains (4) summary
    smart00256
    Location:86120
    FBOX; A Receptor for Ubiquitination Targets
    COG2319
    Location:166411
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:177211
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:166395
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  9. XM_025156036.3XP_025011804.1  F-box/WD repeat-containing protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A8V1AFA0
    Conserved Domains (3) summary
    smart00256
    Location:86120
    FBOX; A Receptor for Ubiquitination Targets
    sd00039
    Location:177211
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:166382
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  10. XM_046901695.1XP_046757651.1  F-box/WD repeat-containing protein 2 isoform X5

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    10392977..10402158 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046928805.1XP_046784761.1  F-box/WD repeat-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    Q5ZK75
  2. XM_046928812.1XP_046784768.1  F-box/WD repeat-containing protein 2 isoform X9

  3. XM_046928810.1XP_046784766.1  F-box/WD repeat-containing protein 2 isoform X7

  4. XM_046928811.1XP_046784767.1  F-box/WD repeat-containing protein 2 isoform X8

  5. XM_046928806.1XP_046784762.1  F-box/WD repeat-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    Q5ZK75
  6. XM_046928803.1XP_046784759.1  F-box/WD repeat-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1A9Z5
  7. XM_046928804.1XP_046784760.1  F-box/WD repeat-containing protein 2 isoform X2

  8. XM_046928807.1XP_046784763.1  F-box/WD repeat-containing protein 2 isoform X4

  9. XM_046928802.1XP_046784758.1  F-box/WD repeat-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1A9Z5
  10. XM_046928809.1XP_046784765.1  F-box/WD repeat-containing protein 2 isoform X6

  11. XM_046928808.1XP_046784764.1  F-box/WD repeat-containing protein 2 isoform X5