CRKL CRK like proto-oncogene, adaptor protein [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: CRKLprovided by CGNC
Official Full Name: CRK like proto-oncogene, adaptor proteinprovided by CGNC
Primary source: CGNC:4810
See related: Ensembl:ENSGALG00010026221
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	15	NC_052546.1 (8267752..8281982, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	15	NC_052587.1 (8278439..8292660, complement)

Chromosome 15 - NC_052546.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of ERK1 and ERK2 cascade	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: crk-like protein

Names: v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

8267752..8281982 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_415233.8 → XP_415233.1 crk-like protein

UniProtKB/TrEMBL

A0A8V1ACY3

Related

ENSGALP00010039346.1, ENSGALT00010063811.1

Conserved Domains (3) summary

cd09926
Location:7 → 107

SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK

cd11758
Location:127 → 181

SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins

cd11759
Location:237 → 293

SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

8278439..8292660 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040684965.2 → XP_040540899.1 crk-like protein

UniProtKB/TrEMBL

A0A8V1ACY3

Conserved Domains (3) summary

cd09926
Location:7 → 107

SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK

cd11758
Location:127 → 181

SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins

cd11759
Location:237 → 293

SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins