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CG9588 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41672, updated on 5-May-2024

Summary

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Official Symbol
CG9588provided by FlyBase
Primary source
FLYBASE:FBgn0038166
Locus tag
Dmel_CG9588
See related
AllianceGenome:FB:FBgn0038166
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
9588; Dmel\CG9588; dp27; p27
Summary
Predicted to be involved in proteasome regulatory particle assembly. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including embryonic brain; embryonic/larval midgut; embryonic/larval nervous system; extended germ band embryo; and visceral muscle primordium. Orthologous to human PSMD9 (proteasome 26S subunit, non-ATPase 9). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
87F7-87F7; 3-54 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (13675092..13676681, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9500814..9502403, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene B52 Neighboring gene TWIK-related acid-sensitive K[+] channel 6 Neighboring gene Lkb1 kinase Neighboring gene oocyte maintenance defects Neighboring gene falafel Neighboring gene uncharacterized protein Neighboring gene flyers-cup

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Accurate gene-tree reconstruction by learning gene- and species-specific substitution rates across multiple complete genomes. Rasmussen MD, et al. Genome Res, 2007 Dec. PMID 17989260, Free PMC Article
  2. The Drosophila Lkb1 kinase is required for spindle formation and asymmetric neuroblast division. Bonaccorsi S, et al. Development, 2007 Jun. PMID 17507418
  3. Proteasome regulation by ADP-ribosylation. Cho-Park PF, et al. Cell, 2013 Apr 25. PMID 23622245, Free PMC Article
  4. On the role of PDZ domain-encoding genes in Drosophila border cell migration. Aranjuez G, et al. G3 (Bethesda), 2012 Nov. PMID 23173089, Free PMC Article
  5. Lethality in Drosophila melanogaster/Drosophila simulans species hybrids is not associated with substantial transcriptional misregulation. Barbash DA, et al. J Exp Zool B Mol Dev Evol, 2007 Jan 15. PMID 17075830

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in proteasome regulatory particle assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteasome regulatory particle assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9588-PA
NP_650301.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    13675092..13676681 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142044.4 → NP_650301.1  uncharacterized protein Dmel_CG9588 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650301.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VFS8
    Related
    FBpp0082314
    Conserved Domains (1) summary
    cd00136
    Location:116 → 186
    PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VFS8.1 Q9VFS8

Gene LinkOut

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