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PRKCB protein kinase C beta [ Gallus gallus (chicken) ]

Gene ID: 416567, updated on 5-Mar-2024

Summary

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Symbol
PRKCBprovided by CGNC
Full Name
protein kinase C betaprovided by CGNC
Primary source
CGNC:50286
See related
Ensembl:ENSGALG00010018355
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
PRKCB1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
18
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 14 NC_052545.1 (6666417..6744488)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 14 NC_052586.1 (6662333..6740450)

Chromosome 14 - NC_052545.1Genomic Context describing neighboring genes Neighboring gene leucine carboxyl methyltransferase 1 Neighboring gene aquaporin 8 Neighboring gene microRNA 1615 Neighboring gene calcium voltage-gated channel auxiliary subunit gamma 3 Neighboring gene uncharacterized LOC107054619

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Protein kinase C isotypes in signal transduction for the 1,25D3-MARRS receptor (ERp57/PDIA3) in steroid hormone-stimulated phosphate uptake. Tunsophon S, et al. Steroids, 2010 Apr. PMID 20079367
  2. Ca2+ influx and protein scaffolding via TRPC3 sustain PKCbeta and ERK activation in B cells. Numaga T, et al. J Cell Sci, 2010 Mar 15. PMID 20179100, Free PMC Article
  3. The phylogenetic relationship of tetrapod, coelacanth, and lungfish revealed by the sequences of forty-four nuclear genes. Takezaki N, et al. Mol Biol Evol, 2004 Aug. PMID 15128875

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PKCalpha and PKCbeta are both involved in steroid-stimulated phosphate uptake.
    Title: Protein kinase C isotypes in signal transduction for the 1,25D3-MARRS receptor (ERp57/PDIA3) in steroid hormone-stimulated phosphate uptake.
  2. TRPC3 functions as both a Ca(2+)-permeable channel and a protein scaffold at the plasma membrane for downstream PKCbeta activation in B cells.
    Title: Ca2+ influx and protein scaffolding via TRPC3 sustain PKCbeta and ERK activation in B cells.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables diacylglycerol-dependent serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein kinase C beta type
Names
protein kinase C, beta 1
XP_015149966.1
XP_015149967.1
XP_040539945.1
XP_040539946.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052545.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    6666417..6744488
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015294481.3 → XP_015149967.1  protein kinase C beta type isoform X2

    UniProtKB/TrEMBL
    A0A1D5PCZ1
    Related
    ENSGALP00010026368.1, ENSGALT00010044315.1
    Conserved Domains (4) summary
    cd04026
    Location:158 → 288
    C2_PKC_alpha_gamma; C2 domain in Protein Kinase C (PKC) alpha and gamma
    cd20833
    Location:34 → 91
    C1_cPKC_rpt1; first protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family
    cd20836
    Location:101 → 154
    C1_cPKC_rpt2; second protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family
    cl21453
    Location:340 → 663
    PKc_like; Protein Kinases, catalytic domain

  2. XM_015294480.4 → XP_015149966.1  protein kinase C beta type isoform X1

    UniProtKB/TrEMBL
    A0A1D5PUY5
    Related
    ENSGALP00010026366.1, ENSGALT00010044313.1
    Conserved Domains (4) summary
    cd04026
    Location:158 → 288
    C2_PKC_alpha_gamma; C2 domain in Protein Kinase C (PKC) alpha and gamma
    cd05616
    Location:340 → 662
    STKc_cPKC_beta; Catalytic domain of the Serine/Threonine Kinase, Classical Protein Kinase C beta
    cd20833
    Location:34 → 91
    C1_cPKC_rpt1; first protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family
    cd20836
    Location:101 → 154
    C1_cPKC_rpt2; second protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052586.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    6662333..6740450
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040684012.2 → XP_040539946.1  protein kinase C beta type isoform X2

    UniProtKB/TrEMBL
    A0A1D5PCZ1
    Conserved Domains (4) summary
    cd04026
    Location:158 → 288
    C2_PKC_alpha_gamma; C2 domain in Protein Kinase C (PKC) alpha and gamma
    cd20833
    Location:34 → 91
    C1_cPKC_rpt1; first protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family
    cd20836
    Location:101 → 154
    C1_cPKC_rpt2; second protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family
    cl21453
    Location:340 → 663
    PKc_like; Protein Kinases, catalytic domain

  2. XM_040684011.2 → XP_040539945.1  protein kinase C beta type isoform X1

    UniProtKB/TrEMBL
    A0A1D5PUY5
    Conserved Domains (4) summary
    cd04026
    Location:158 → 288
    C2_PKC_alpha_gamma; C2 domain in Protein Kinase C (PKC) alpha and gamma
    cd05616
    Location:340 → 662
    STKc_cPKC_beta; Catalytic domain of the Serine/Threonine Kinase, Classical Protein Kinase C beta
    cd20833
    Location:34 → 91
    C1_cPKC_rpt1; first protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family
    cd20836
    Location:101 → 154
    C1_cPKC_rpt2; second protein kinase C conserved region 1 (C1 domain) found in the classical (or conventional) protein kinase C (cPKC) family
Nucleotide Protein
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