PTTG2 pituitary tumor-transforming 2 [Gallus gallus (chicken)] - Gene

Summary

Symbol: PTTG2provided by CGNC
Full Name: pituitary tumor-transforming 2provided by CGNC
Primary source: CGNC:50178
See related: Ensembl:ENSGALG00010009078
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: PTTG1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	13	NC_052544.1 (7440253..7443251, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	13	NC_052585.1 (7444593..7447591, complement)

Chromosome 13 - NC_052544.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in chromosome organization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: securin

Names: pituitary tumor-transforming 1; pituitary tumor-transforming protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001277740.2 → NP_001264669.2 securin isoform 1

Status: VALIDATED

Description

Transcript Variant: This variant (1) encodes the longer isoform (1).

Source sequence(s)

JAENSK010000256

UniProtKB/TrEMBL

A0A8V0Y044

Related

ENSGALP00010012326.1, ENSGALT00010021630.1

Conserved Domains (1) summary

pfam04856
Location:1 → 171

Securin; Securin sister-chromatid separation inhibitor
NM_001277741.2 → NP_001264670.2 securin isoform 2

Status: VALIDATED

Description

Transcript Variant: This variant (2) lacks an internal exon in the 5' region, which results in the use of an alternate start codon, and has an alternate splice site in the central region, compared to variant 1. The resulting isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1.

Source sequence(s)

JAENSK010000256

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

7440253..7443251 complement

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GenBank, FASTA, Sequence Viewer (Graphics)