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APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 [ Gallus gallus (chicken) ]

Gene ID: 416002, updated on 5-Mar-2024

Summary

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Symbol
APPL1provided by CGNC
Full Name
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1provided by CGNC
Primary source
CGNC:4118
See related
Ensembl:ENSGALG00010027052
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
22
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 12 NC_052543.1 (8791388..8821046)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 12 NC_052584.1 (8818672..8848282)

Chromosome 12 - NC_052543.1Genomic Context describing neighboring genes Neighboring gene interleukin 17 receptor D Neighboring gene HESX homeobox 1 Neighboring gene ankyrin repeat and SOCS box containing 14 Neighboring gene dynein, axonemal, heavy chain 12 Neighboring gene phosphodiesterase 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DCC-interacting protein 13-alpha
Names
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052543.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    8791388..8821046
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004944584.5 → XP_004944641.2  DCC-interacting protein 13-alpha

    UniProtKB/TrEMBL
    A0A8V1A6X4, A0A8V1A9G6
    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:488 → 623
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

  2. XM_414344.8 → XP_414344.5  DCC-interacting protein 13-alpha

    UniProtKB/TrEMBL
    A0A8V1A6X4, A0A8V1A9G6
    Related
    ENSGALP00010039872.1, ENSGALT00010065591.1
    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:488 → 623
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052584.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    8818672..8848282
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040682285.2 → XP_040538219.1  DCC-interacting protein 13-alpha

    UniProtKB/TrEMBL
    A0A8V1A6X4, A0A8V1A9G6
    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:488 → 623
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

  2. XM_040682286.2 → XP_040538220.1  DCC-interacting protein 13-alpha

    UniProtKB/TrEMBL
    A0A8V1A6X4, A0A8V1A9G6
    Conserved Domains (3) summary
    cd07631
    Location:20 → 234
    BAR_APPL1; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 1
    cd13158
    Location:488 → 623
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
Nucleotide Protein
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