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MAP2K1 mitogen-activated protein kinase kinase 1 [ Gallus gallus (chicken) ]

Gene ID: 415549, updated on 3-Apr-2024

Summary

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Symbol
MAP2K1provided by CGNC
Full Name
mitogen-activated protein kinase kinase 1provided by CGNC
Primary source
CGNC:50013
See related
Ensembl:ENSGALG00010018000
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (18496305..18527713)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (18361134..18392733)

Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene DIS3 like exosome 3'-5' exoribonuclease Neighboring gene small Cajal body-specific RNA 14 Neighboring gene TIMELESS interacting protein Neighboring gene small nucleolar RNA SNORD18 Neighboring gene small nuclear RNA activating complex polypeptide 5 Neighboring gene ribosomal protein L4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles. Eisenhardt AE, et al. Oncotarget, 2016 May 3. PMID 27034005, Free PMC Article
  2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity mitogen-activated protein kinase kinase 1
Names
MAP kinase kinase 1
NP_001005830.1
XP_015147582.1
XP_046780871.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005830.2 → NP_001005830.1  dual specificity mitogen-activated protein kinase kinase 1

    See identical proteins and their annotated locations for NP_001005830.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000246
    UniProtKB/TrEMBL
    A0A8V0Z5Q1, Q5ZIF0
    Related
    ENSGALP00010025882.1, ENSGALT00010043524.1
    Conserved Domains (1) summary
    cd06650
    Location:62 → 382
    PKc_MEK1; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase 1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    18496305..18527713
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015292096.4 → XP_015147582.1  dual specificity mitogen-activated protein kinase kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A1L1RPJ2, A0A8V0Z5Q1
    Related
    ENSGALP00010025870.1, ENSGALT00010043511.1
    Conserved Domains (2) summary
    smart00220
    Location:62 → 357
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06650
    Location:56 → 376
    PKc_MEK1; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase 1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    18361134..18392733
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046924915.1 → XP_046780871.1  dual specificity mitogen-activated protein kinase kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A1L1RPJ2
Nucleotide Protein Strain
Heading Accession and Version

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