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AKAP13 A-kinase anchoring protein 13 [ Gallus gallus (chicken) ]

Gene ID: 415502, updated on 3-Apr-2024

Summary

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Official Symbol
AKAP13provided by CGNC
Official Full Name
A-kinase anchoring protein 13provided by CGNC
Primary source
CGNC:49999
See related
Ensembl:ENSGALG00010020117
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
50
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (13984259..14178852, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (13861993..14056682, complement)

Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene neurotrophic receptor tyrosine kinase 3 Neighboring gene uncharacterized LOC107054206 Neighboring gene uncharacterized LOC112533196 Neighboring gene ATP/GTP binding protein like 1 Neighboring gene kelch like family member 25 Neighboring gene uncharacterized LOC121111581 Neighboring gene synaptic vesicle glycoprotein 2B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MAP-kinase scaffold activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adrenergic receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
A-kinase anchor protein 13
Names
A kinase (PRKA) anchor protein 13

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    13984259..14178852 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046899348.1 → XP_046755304.1  A-kinase anchor protein 13 isoform X8

  2. XM_046899343.1 → XP_046755299.1  A-kinase anchor protein 13 isoform X3

  3. XM_046899346.1 → XP_046755302.1  A-kinase anchor protein 13 isoform X6

    Related
    ENSGALP00010028692.1, ENSGALT00010048601.1

  4. XM_046899344.1 → XP_046755300.1  A-kinase anchor protein 13 isoform X4

  5. XM_046899347.1 → XP_046755303.1  A-kinase anchor protein 13 isoform X7

  6. XM_046899342.1 → XP_046755298.1  A-kinase anchor protein 13 isoform X2

  7. XM_046899345.1 → XP_046755301.1  A-kinase anchor protein 13 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZBV8
    Related
    ENSGALP00010028699.1, ENSGALT00010048608.1

  8. XM_046899337.1 → XP_046755293.1  A-kinase anchor protein 13 isoform X1

  9. XM_046899338.1 → XP_046755294.1  A-kinase anchor protein 13 isoform X1

  10. XM_046899339.1 → XP_046755295.1  A-kinase anchor protein 13 isoform X1

  11. XM_046899340.1 → XP_046755296.1  A-kinase anchor protein 13 isoform X1

  12. XM_046899349.1 → XP_046755305.1  A-kinase anchor protein 13 isoform X9

  13. XM_046899350.1 → XP_046755306.1  A-kinase anchor protein 13 isoform X10

  14. XM_046899352.1 → XP_046755308.1  A-kinase anchor protein 13 isoform X12

    Related
    ENSGALP00010028683.1, ENSGALT00010048593.1

  15. XM_046899353.1 → XP_046755309.1  A-kinase anchor protein 13 isoform X12

  16. XM_040706420.2 → XP_040562354.1  A-kinase anchor protein 13 isoform X15

    UniProtKB/TrEMBL
    A0A8V0ZBT3
    Conserved Domains (6) summary
    COG1196
    Location:877 → 1221
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    PRK12704
    Location:1115 → 1223
    PRK12704; phosphodiesterase; Provisional
    cd00160
    Location:547 → 741
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13392
    Location:784 → 886
    PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
    pfam17380
    Location:1090 → 1311
    DUF5401; Family of unknown function (DUF5401)
    cl00040
    Location:347 → 387
    C1; protein kinase C conserved region 1 (C1 domain) superfamily

  17. XM_040706419.2 → XP_040562353.1  A-kinase anchor protein 13 isoform X14

    UniProtKB/TrEMBL
    A0A8V0ZBT3
    Related
    ENSGALP00010028674.1, ENSGALT00010048583.1
    Conserved Domains (6) summary
    COG1196
    Location:929 → 1273
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    PRK12704
    Location:1167 → 1275
    PRK12704; phosphodiesterase; Provisional
    cd00160
    Location:599 → 793
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13392
    Location:836 → 938
    PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
    pfam17380
    Location:1142 → 1363
    DUF5401; Family of unknown function (DUF5401)
    cl00040
    Location:399 → 439
    C1; protein kinase C conserved region 1 (C1 domain) superfamily

  18. XM_040706418.2 → XP_040562352.1  A-kinase anchor protein 13 isoform X13

    UniProtKB/TrEMBL
    A0A8V0ZBT3
    Related
    ENSGALP00010028676.1, ENSGALT00010048585.1
    Conserved Domains (6) summary
    COG1196
    Location:930 → 1274
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    PRK12704
    Location:1168 → 1276
    PRK12704; phosphodiesterase; Provisional
    cd00160
    Location:600 → 794
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13392
    Location:837 → 939
    PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
    pfam17380
    Location:1143 → 1364
    DUF5401; Family of unknown function (DUF5401)
    cl00040
    Location:400 → 440
    C1; protein kinase C conserved region 1 (C1 domain) superfamily

  19. XM_040706417.2 → XP_040562351.1  A-kinase anchor protein 13 isoform X11

    UniProtKB/TrEMBL
    A0A8V0ZBT3
    Conserved Domains (6) summary
    COG1196
    Location:969 → 1313
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    PRK12704
    Location:1207 → 1315
    PRK12704; phosphodiesterase; Provisional
    cd00160
    Location:639 → 833
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13392
    Location:876 → 978
    PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
    pfam17380
    Location:1182 → 1403
    DUF5401; Family of unknown function (DUF5401)
    cl00040
    Location:439 → 479
    C1; protein kinase C conserved region 1 (C1 domain) superfamily

  20. XM_025154078.3 → XP_025009846.2  A-kinase anchor protein 13 isoform X16

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    13861993..14056682 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046925084.1 → XP_046781040.1  A-kinase anchor protein 13 isoform X6

  2. XM_046925076.1 → XP_046781032.1  A-kinase anchor protein 13 isoform X1

  3. XM_046925086.1 → XP_046781042.1  A-kinase anchor protein 13 isoform X8

  4. XM_046925079.1 → XP_046781035.1  A-kinase anchor protein 13 isoform X3

  5. XM_046925083.1 → XP_046781039.1  A-kinase anchor protein 13 isoform X6

  6. XM_046925081.1 → XP_046781037.1  A-kinase anchor protein 13 isoform X4

  7. XM_046925085.1 → XP_046781041.1  A-kinase anchor protein 13 isoform X7

  8. XM_046925078.1 → XP_046781034.1  A-kinase anchor protein 13 isoform X2

  9. XM_046925082.1 → XP_046781038.1  A-kinase anchor protein 13 isoform X5

  10. XM_046925073.1 → XP_046781029.1  A-kinase anchor protein 13 isoform X1

  11. XM_046925074.1 → XP_046781030.1  A-kinase anchor protein 13 isoform X1

  12. XM_046925075.1 → XP_046781031.1  A-kinase anchor protein 13 isoform X1

  13. XM_046925077.1 → XP_046781033.1  A-kinase anchor protein 13 isoform X1

  14. XM_046925087.1 → XP_046781043.1  A-kinase anchor protein 13 isoform X9

  15. XM_046925088.1 → XP_046781044.1  A-kinase anchor protein 13 isoform X10

  16. XM_046925089.1 → XP_046781045.1  A-kinase anchor protein 13 isoform X12

  17. XM_046925091.1 → XP_046781047.1  A-kinase anchor protein 13 isoform X12

  18. XM_040679824.2 → XP_040535758.1  A-kinase anchor protein 13 isoform X15

    UniProtKB/TrEMBL
    A0A8V0ZBT3
    Conserved Domains (6) summary
    COG1196
    Location:877 → 1221
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    PRK12704
    Location:1115 → 1223
    PRK12704; phosphodiesterase; Provisional
    cd00160
    Location:547 → 741
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13392
    Location:784 → 886
    PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
    pfam17380
    Location:1090 → 1311
    DUF5401; Family of unknown function (DUF5401)
    cl00040
    Location:347 → 387
    C1; protein kinase C conserved region 1 (C1 domain) superfamily

  19. XM_040679822.2 → XP_040535756.1  A-kinase anchor protein 13 isoform X14

    UniProtKB/TrEMBL
    A0A8V0ZBT3
    Conserved Domains (6) summary
    COG1196
    Location:929 → 1273
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    PRK12704
    Location:1167 → 1275
    PRK12704; phosphodiesterase; Provisional
    cd00160
    Location:599 → 793
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13392
    Location:836 → 938
    PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
    pfam17380
    Location:1142 → 1363
    DUF5401; Family of unknown function (DUF5401)
    cl00040
    Location:399 → 439
    C1; protein kinase C conserved region 1 (C1 domain) superfamily

  20. XM_040679821.2 → XP_040535755.1  A-kinase anchor protein 13 isoform X13

    UniProtKB/TrEMBL
    A0A8V0ZBT3
    Conserved Domains (6) summary
    COG1196
    Location:930 → 1274
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    PRK12704
    Location:1168 → 1276
    PRK12704; phosphodiesterase; Provisional
    cd00160
    Location:600 → 794
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13392
    Location:837 → 939
    PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
    pfam17380
    Location:1143 → 1364
    DUF5401; Family of unknown function (DUF5401)
    cl00040
    Location:400 → 440
    C1; protein kinase C conserved region 1 (C1 domain) superfamily

  21. XM_040679820.2 → XP_040535754.1  A-kinase anchor protein 13 isoform X11

    UniProtKB/TrEMBL
    A0A8V0ZBT3
    Conserved Domains (6) summary
    COG1196
    Location:969 → 1313
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    PRK12704
    Location:1207 → 1315
    PRK12704; phosphodiesterase; Provisional
    cd00160
    Location:639 → 833
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13392
    Location:876 → 978
    PH_AKAP13; A-kinase anchoring protein 13 Pleckstrin homology (PH) domain
    pfam17380
    Location:1182 → 1403
    DUF5401; Family of unknown function (DUF5401)
    cl00040
    Location:439 → 479
    C1; protein kinase C conserved region 1 (C1 domain) superfamily

  22. XM_040679825.2 → XP_040535759.1  A-kinase anchor protein 13 isoform X16

Nucleotide Protein Strain
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