U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PDE8A phosphodiesterase 8A [ Gallus gallus (chicken) ]

Gene ID: 415455, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Symbol
PDE8Aprovided by CGNC
Full Name
phosphodiesterase 8Aprovided by CGNC
Primary source
CGNC:4485
See related
Ensembl:ENSGALG00010020912
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 10
Exon count:
31
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (10945556..11087058)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (10818982..10960450)

Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene histidine decarboxylase Neighboring gene glycine amidinotransferase Neighboring gene uncharacterized LOC112533163 Neighboring gene uncharacterized LOC121111635 Neighboring gene small Cajal body-specific RNA 15 Neighboring gene fibronectin type III and SPRY domain containing 2 Neighboring gene uncharacterized LOC124417114 Neighboring gene WAS protein homolog associated with actin, golgi membranes and microtubules Neighboring gene homer scaffolding protein 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to epidermal growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
XP_040536232.1
XP_040536233.1
XP_040536234.1
XP_040562700.1
XP_040562701.1
XP_040562702.1
XP_046755101.1
XP_046755102.1
XP_046755103.1
XP_046755104.1
XP_046755105.1
XP_046755106.1
XP_046755107.1
XP_046755108.1
XP_046781002.1
XP_046781004.1
XP_046781005.1
XP_046781006.1
XP_046781007.1
XP_046781008.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    10945556..11087058
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046899148.1 → XP_046755104.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZF07
    Related
    ENSGALP00010029844.1, ENSGALT00010050554.1

  2. XM_040706767.1 → XP_040562701.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF02
    Conserved Domains (4) summary
    COG2202
    Location:140 → 350
    PAS; PAS domain [Signal transduction mechanisms]
    pfam00233
    Location:581 → 832
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08629
    Location:1 → 51
    PDE8; PDE8 phosphodiesterase
    pfam13426
    Location:252 → 350
    PAS_9; PAS domain

  3. XM_040706766.1 → XP_040562700.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF02
    Conserved Domains (4) summary
    COG2202
    Location:140 → 350
    PAS; PAS domain [Signal transduction mechanisms]
    pfam00233
    Location:581 → 832
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08629
    Location:1 → 51
    PDE8; PDE8 phosphodiesterase
    pfam13426
    Location:252 → 350
    PAS_9; PAS domain

  4. XM_040706768.1 → XP_040562702.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF02
    Conserved Domains (4) summary
    COG2202
    Location:140 → 350
    PAS; PAS domain [Signal transduction mechanisms]
    pfam00233
    Location:581 → 832
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08629
    Location:1 → 51
    PDE8; PDE8 phosphodiesterase
    pfam13426
    Location:252 → 350
    PAS_9; PAS domain

  5. XM_046899147.1 → XP_046755103.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF02

  6. XM_046899146.1 → XP_046755102.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF02
    Related
    ENSGALP00010029839.1, ENSGALT00010050548.1

  7. XM_046899145.1 → XP_046755101.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF02

  8. XM_046899151.1 → XP_046755107.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X4

  9. XM_046899150.1 → XP_046755106.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X4

  10. XM_046899149.1 → XP_046755105.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X3

  11. XM_046899152.1 → XP_046755108.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X4

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    10818982..10960450
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046925050.1 → XP_046781006.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X2

  2. XM_040680299.2 → XP_040536233.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF02
    Conserved Domains (4) summary
    COG2202
    Location:140 → 350
    PAS; PAS domain [Signal transduction mechanisms]
    pfam00233
    Location:581 → 832
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08629
    Location:1 → 51
    PDE8; PDE8 phosphodiesterase
    pfam13426
    Location:252 → 350
    PAS_9; PAS domain

  3. XM_040680298.2 → XP_040536232.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF02
    Conserved Domains (4) summary
    COG2202
    Location:140 → 350
    PAS; PAS domain [Signal transduction mechanisms]
    pfam00233
    Location:581 → 832
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08629
    Location:1 → 51
    PDE8; PDE8 phosphodiesterase
    pfam13426
    Location:252 → 350
    PAS_9; PAS domain

  4. XM_040680300.2 → XP_040536234.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF02
    Conserved Domains (4) summary
    COG2202
    Location:140 → 350
    PAS; PAS domain [Signal transduction mechanisms]
    pfam00233
    Location:581 → 832
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08629
    Location:1 → 51
    PDE8; PDE8 phosphodiesterase
    pfam13426
    Location:252 → 350
    PAS_9; PAS domain

  5. XM_046925049.1 → XP_046781005.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF02

  6. XM_046925048.1 → XP_046781004.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF02

  7. XM_046925046.1 → XP_046781002.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZF02

  8. XM_046925052.1 → XP_046781008.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X4

  9. XM_046925051.1 → XP_046781007.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X3

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.