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FGF7 fibroblast growth factor 7 [ Gallus gallus (chicken) ]

Gene ID: 415439, updated on 5-Mar-2024

Summary

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Symbol
FGF7provided by CGNC
Full Name
fibroblast growth factor 7provided by CGNC
Primary source
CGNC:66242
See related
Ensembl:ENSGALG00010016094
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (10561115..10592011)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (10434364..10463349)

Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene galactokinase 2 Neighboring gene family with sequence similarity 227 member B Neighboring gene uncharacterized LOC107054189 Neighboring gene DTW domain containing 1 Neighboring gene spermatogenesis associated 5 like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. FGF signaling segregates biliary cell-lineage from chick hepatoblasts cooperatively with BMP4 and ECM components in vitro. Yanai M, et al. Dev Dyn, 2008 May. PMID 18393311
  2. Expression of Fgf10 and Fgf receptors during development of the embryonic chicken stomach. Shin M, et al. Gene Expr Patterns, 2005 Apr. PMID 15749079
  3. Cloning and expression analysis of Fgf5, 6 and 7 during early chick development. Kumar M, et al. Gene Expr Patterns, 2012 Aug-Sep. PMID 22634565, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Fgf6 and Fgf7, although belonging to different subfamilies with diverged sequences, are expressed in similar patterns within the mesoderm
    Title: Cloning and expression analysis of Fgf5, 6 and 7 during early chick development.
  2. These data strongly suggest that bFGF and FGF7 promote biliary epithelial cell differentiation cooperatively with BMP4 and extracellular matrix in vivo.
    Title: FGF signaling segregates biliary cell-lineage from chick hepatoblasts cooperatively with BMP4 and ECM components in vitro.
  3. FGF receptors are expressed only in epithelia of the embryonic digestive tract.
    Title: Expression of Fgf10 and Fgf receptors during development of the embryonic chicken stomach.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables type 2 fibroblast growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in animal organ morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lung development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epithelial cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibroblast growth factor 7
Names
fibroblast growth factor 7 (keratinocyte growth factor)
keratinocyte growth factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012525.1 → NP_001012543.1  fibroblast growth factor 7

    See identical proteins and their annotated locations for NP_001012543.1

    Status: PROVISIONAL

    Source sequence(s)
    AB193566
    UniProtKB/TrEMBL
    Q5KRA4, R4GL03
    Conserved Domains (1) summary
    pfam00167
    Location:65 → 189
    FGF; Fibroblast growth factor

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    10561115..10592011
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015291987.4 → XP_015147473.1  fibroblast growth factor 7 isoform X2

    UniProtKB/TrEMBL
    Q5KRA4, R4GL03
    Related
    ENSGALP00010022382.1, ENSGALT00010038699.1
    Conserved Domains (1) summary
    pfam00167
    Location:65 → 189
    FGF; Fibroblast growth factor

  2. XM_015291985.4 → XP_015147471.1  fibroblast growth factor 7 isoform X1

    Conserved Domains (1) summary
    pfam00167
    Location:71 → 195
    FGF; Fibroblast growth factor

  3. XM_015291989.4 → XP_015147475.1  fibroblast growth factor 7 isoform X3

    Conserved Domains (1) summary
    pfam00167
    Location:48 → 172
    FGF; Fibroblast growth factor

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    10434364..10463349
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046924831.1 → XP_046780787.1  fibroblast growth factor 7 isoform X2

    UniProtKB/TrEMBL
    Q5KRA4, R4GL03

  2. XM_046924830.1 → XP_046780786.1  fibroblast growth factor 7 isoform X1

  3. XM_046924832.1 → XP_046780788.1  fibroblast growth factor 7 isoform X3

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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