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SIN3A SIN3 transcription regulator family member A [ Gallus gallus (chicken) ]

Gene ID: 415307, updated on 5-Mar-2024

Summary

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Symbol
SIN3Aprovided by CGNC
Full Name
SIN3 transcription regulator family member Aprovided by CGNC
Primary source
CGNC:1146
See related
Ensembl:ENSGALG00010021407
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
24
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (2684339..2709659, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (2556975..2582253, complement)

Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene nei like DNA glycosylase 1 Neighboring gene mannosidase alpha class 2C member 1 Neighboring gene uncharacterized LOC121111651 Neighboring gene protein tyrosine phosphatase, non-receptor type 9 Neighboring gene snurportin 1 Neighboring gene microRNA 6575

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Chick Hairy1 protein interacts with Sap18, a component of the Sin3/HDAC transcriptional repressor complex. Sheeba CJ, et al. BMC Dev Biol, 2007 Jul 10. PMID 17623094, Free PMC Article
  2. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
paired amphipathic helix protein Sin3a
Names
SIN3 homolog A, transcription regulator
SIN3 transcription regulator homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001293184.3 → NP_001280113.1  paired amphipathic helix protein Sin3a

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000245
    UniProtKB/TrEMBL
    E1BX21
    Related
    ENSGALP00010030948.1, ENSGALT00010051875.1
    Conserved Domains (1) summary
    COG5602
    Location:5 → 1214
    Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2684339..2709659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015278820.4 → XP_015134306.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    E1BX21
    Conserved Domains (1) summary
    COG5602
    Location:5 → 1214
    Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

  2. XM_025153811.3 → XP_025009579.1  paired amphipathic helix protein Sin3a isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZJI8
    Related
    ENSGALP00010030961.1, ENSGALT00010051893.1
    Conserved Domains (1) summary
    cl07053
    Location:5 → 1208
    Sin3_corepress; Sin3 family co-repressor

  3. XM_040706252.2 → XP_040562186.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    E1BX21
    Conserved Domains (1) summary
    COG5602
    Location:5 → 1214
    Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

  4. XM_015278821.3 → XP_015134307.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    E1BX21
    Conserved Domains (1) summary
    COG5602
    Location:5 → 1214
    Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2556975..2582253 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046924656.1 → XP_046780612.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    E1BX21

  2. XM_046924655.1 → XP_046780611.1  paired amphipathic helix protein Sin3a isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZJI8

  3. XM_046924658.1 → XP_046780614.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    E1BX21

  4. XM_046924657.1 → XP_046780613.1  paired amphipathic helix protein Sin3a isoform X2

    UniProtKB/TrEMBL
    E1BX21
Nucleotide Protein Strain
Heading Accession and Version

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