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Rbp1 RNA-binding protein 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41294, updated on 10-May-2024

Summary

Official Symbol
Rbp1provided by FlyBase
Official Full Name
RNA-binding protein 1provided by FlyBase
Primary source
FLYBASE:FBgn0260944
Locus tag
Dmel_CG17136
See related
AllianceGenome:FB:FBgn0260944
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17136; Dmel\CG17136; Rbp-1; rbp1; RBP1; Rbp11; Rbp1D; rrm1; RRM1; rrm11; RRM11; SRSF3
Summary
Enables mRNA binding activity. Involved in mRNA cis splicing, via spliceosome and regulation of RNA metabolic process. Located in nucleus and transcriptionally active chromatin. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; extended germ band embryo; foregut primordium; and gut section. Orthologous to human SRSF3 (serine and arginine rich splicing factor 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
86C6-86C6; 3-50 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10784383..10786465)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (6610105..6612187)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein L37 Neighboring gene Arginine methyltransferase 1 Neighboring gene Minichromosome maintenance 5

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of euchromatin IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
RNA-binding protein 1
Names
CG17136-PA
CG17136-PD
RNA-binding protein 11
Rbp1-PA
Rbp1-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    10784383..10786465
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_169364.3NP_731510.1  RNA-binding protein 1, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731510.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V2P0, Q02427, Q26271, Q26280, Q8T9K6, Q9VGW8
    Related
    FBpp0081754
    Conserved Domains (1) summary
    cd12373
    Location:1281
    RRM_SRSF3_like; RNA recognition motif (RRM) found in serine/arginine-rich splicing factor 3 (SRSF3) and similar proteins
  2. NM_079583.3NP_524307.1  RNA-binding protein 1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524307.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1B2AJY5
    Related
    FBpp0081752
    Conserved Domains (1) summary
    cd12373
    Location:1281
    RRM_SRSF3_like; RNA recognition motif (RRM) found in serine/arginine-rich splicing factor 3 (SRSF3) and similar proteins