U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

EGF epidermal growth factor [ Gallus gallus (chicken) ]

Gene ID: 408035, updated on 3-Apr-2024

Summary

Symbol
EGFprovided by CGNC
Full Name
epidermal growth factorprovided by CGNC
Primary source
CGNC:9223
See related
Ensembl:ENSGALG00010003806
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: 4
Exon count:
26
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (57538194..57597620, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (57541169..57600670, complement)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110595 Neighboring gene ELOVL fatty acid elongase 6 Neighboring gene leucine rich repeat, Ig-like and transmembrane domains 3 Neighboring gene retinal pigment epithelium-derived rhodopsin homolog Neighboring gene GAR1 ribonucleoprotein

Genomic regions, transcripts, and products

Pathways from PubChem

General protein information

Preferred Names
pro-epidermal growth factor
Names
epidermal growth factor (beta-urogastrone)

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001292.2NP_001001292.2  pro-epidermal growth factor precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000074
    UniProtKB/TrEMBL
    A0A8V0XLN7
    Related
    ENSGALP00010005154.1, ENSGALT00010008810.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    57538194..57597620 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046939964.1XP_046795920.1  pro-epidermal growth factor isoform X1

  2. XM_015276164.3XP_015131650.2  pro-epidermal growth factor isoform X2

    UniProtKB/TrEMBL
    Q6PPB4
    Conserved Domains (5) summary
    PHA03099
    Location:771839
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    smart00135
    Location:450492
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:696737
    EGF_CA; Calcium-binding EGF-like domain
    pfam07645
    Location:738769
    EGF_CA; Calcium-binding EGF domain
    cl00057
    Location:167210
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

RNA

  1. XR_005859117.2 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    57541169..57600670 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046915649.1XP_046771605.1  pro-epidermal growth factor isoform X1

  2. XM_046915651.1XP_046771607.1  pro-epidermal growth factor isoform X2

RNA

  1. XR_006934340.1 RNA Sequence