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SmD2 Small ribonucleoprotein particle protein SmD2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40781, updated on 10-May-2024

Summary

Official Symbol
SmD2provided by FlyBase
Official Full Name
Small ribonucleoprotein particle protein SmD2provided by FlyBase
Primary source
FLYBASE:FBgn0261789
Locus tag
Dmel_CG1249
See related
AllianceGenome:FB:FBgn0261789
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:LD03002; CG1249; D2-Sm; dD2; Dmel\CG1249; Smd2; SMD2_DROME; snRNP D2; snRNP2
Summary
Predicted to enable RNA binding activity. Involved in mitotic cell cycle. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Orthologous to human SNRPD2 (small nuclear ribonucleoprotein D2 polypeptide). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
83E4-83E4; 3-47.5 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6345000..6345911, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2170722..2171633, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Hormone receptor 83

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA splicing, via spliceosome IC
Inferred by Curator
more info
PubMed 
involved_in mRNA splicing, via spliceosome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in mitotic cell cycle HMP PubMed 
involved_in spliceosomal snRNP assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of U1 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U2 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U4/U6 x U5 tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U5 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of catalytic step 2 spliceosome HDA PubMed 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of pICln-Sm protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of precatalytic spliceosome HDA PubMed 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of small nuclear ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
part_of small nuclear ribonucleoprotein complex ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
part_of spliceosomal complex ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 

General protein information

Preferred Names
small ribonucleoprotein particle protein SmD2
Names
CG1249-PA
SmD2-PA
small ribonucleoprotein particle protein D2
snRNP2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    6345000..6345911 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141388.4NP_649645.1  small ribonucleoprotein particle protein SmD2 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649645.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VI10
    UniProtKB/TrEMBL
    A0A1B2AJC2
    Related
    FBpp0081234
    Conserved Domains (1) summary
    cd01720
    Location:23112
    Sm_D2; Sm protein D2