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tfdp1a transcription factor Dp-1, a [ Danio rerio (zebrafish) ]

Gene ID: 406813, updated on 11-Apr-2024

Summary

Official Symbol
tfdp1aprovided by ZNC
Official Full Name
transcription factor Dp-1, aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2883
See related
Ensembl:ENSDARG00000019293 AllianceGenome:ZFIN:ZDB-GENE-040426-2883
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
tfdp1l; zgc:55487; wu:fb94b07; wu:fc52a06
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to contribute to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of cell cycle and regulation of transcription, DNA-templated. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Orthologous to several human genes including TFDP1 (transcription factor Dp-1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 9
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (34950941..34968650)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (35141756..35159463)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene cell division cycle 16 homolog (S. cerevisiae) Neighboring gene DCN1, defective in cullin neddylation 1, domain containing 2a Neighboring gene methyltransferase 21C, AARS1 lysine b Neighboring gene si:ch211-160b11.4

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
contributes_to RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
RNA-binding protein MEX3A; transcription factor Dp-1a
Names
transcription factor Dp-1, like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213492.2NP_998657.1  transcription factor Dp-1a

    See identical proteins and their annotated locations for NP_998657.1

    Status: VALIDATED

    Source sequence(s)
    CR936415
    UniProtKB/TrEMBL
    B2GT80, Q803N1
    Related
    ENSDARP00000072266.4, ENSDART00000077800.6
    Conserved Domains (3) summary
    cd14458
    Location:198244
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:115193
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:200339
    DP; Transcription factor DP

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    34950941..34968650
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009304816.2XP_009303091.1  RNA-binding protein MEX3A isoform X1

    See identical proteins and their annotated locations for XP_009303091.1

    UniProtKB/TrEMBL
    B2GT80, Q803N1
    Conserved Domains (3) summary
    cd14458
    Location:198244
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:115193
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:200339
    DP; Transcription factor DP
  2. XM_005167824.4XP_005167881.1  RNA-binding protein MEX3A isoform X1

    See identical proteins and their annotated locations for XP_005167881.1

    UniProtKB/TrEMBL
    B2GT80, Q803N1
    Conserved Domains (3) summary
    cd14458
    Location:198244
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:115193
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:200339
    DP; Transcription factor DP

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394760.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    241548..259296
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)