U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cstf3 cleavage stimulation factor, 3' pre-RNA, subunit 3 [ Danio rerio (zebrafish) ]

Gene ID: 406326, updated on 27-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
cstf3provided by ZNC
Official Full Name
cleavage stimulation factor, 3' pre-RNA, subunit 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-1997
See related
Ensembl:ENSDARG00000018904 AllianceGenome:ZFIN:ZDB-GENE-040426-1997
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:56028; wu:fa99c02; wu:fb18b09
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in RNA 3'-end processing. Predicted to act upstream of or within mRNA processing. Predicted to be active in nucleus. Orthologous to human CSTF3 (cleavage stimulation factor subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 18
Exon count:
21
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (45734290..45761868, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (45737464..45765042, complement)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene glutamine and serine rich 1 Neighboring gene DEP domain containing 7, paralog a Neighboring gene uncharacterized LOC606627 Neighboring gene si:dkey-34o23.3

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Regulatory back-up circuit of medaka Wt1 co-orthologs ensures PGC maintenance. Klüver N, et al. Dev Biol, 2009 Jan 1. PMID 18992736
  2. Evolution of the vertebrate Pax4/6 class of genes with focus on its novel member, the Pax10 gene. Feiner N, et al. Genome Biol Evol, 2014 Jun 19. PMID 24951566, Free PMC Article
  3. Online automated in vivo zebrafish phosphoproteomics: from large-scale analysis down to a single embryo. Lemeer S, et al. J Proteome Res, 2008 Apr. PMID 18307296
  4. TIF1gamma controls erythroid cell fate by regulating transcription elongation. Bai X, et al. Cell, 2010 Jul 9. PMID 20603019, Free PMC Article
  5. Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development. Iwanami N, et al. Cell Rep, 2016 Nov 22. PMID 27880902, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in RNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within RNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mRNA 3'-end processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
cleavage stimulation factor subunit 3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213053.2 → NP_998218.2  cleavage stimulation factor subunit 3

    Status: VALIDATED

    Source sequence(s)
    BC045871, DT871999, EB848641, EH433088, EH459092
    UniProtKB/TrEMBL
    A0A8M1PEH9, F1QIB2, Q7ZVG5
    Related
    ENSDARP00000003969.7, ENSDART00000025423.9
    Conserved Domains (4) summary
    smart00386
    Location:45 → 77
    HAT; HAT (Half-A-TPR) repeats
    COG5107
    Location:1 → 515
    RNA14; Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor [RNA processing and modification]
    sd00006
    Location:31 → 60
    TPR; TPR repeat [structural motif]
    pfam05843
    Location:375 → 648
    Suf; Suppressor of forked protein (Suf)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    45734290..45761868 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous