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VASP vasodilator stimulated phosphoprotein [ Canis lupus familiaris (dog) ]

Gene ID: 403936, updated on 5-Mar-2024

Summary

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Gene symbol
VASP
Gene description
vasodilator stimulated phosphoprotein
See related
Ensembl:ENSCAFG00845005094
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (110582754..110595760, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (109534415..109547108, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (110762040..110774746, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (110258575..110271274, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (109892681..109905376, complement)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 4 Neighboring gene outer mitochondrial membrane lipid metabolism regulator OPA3 Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1N (putative) Neighboring gene reticulon 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Herpes simplex virus type 1 entry into epithelial MDCKII cells: role of VASP activities. Jaeger V, et al. J Gen Virol, 2010 Sep. PMID 20463151
  2. Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP. Haffner C, et al. EMBO J, 1995 Jan 3. PMID 7828592, Free PMC Article
  3. VASP, zyxin and TES are tension-dependent members of Focal Adherens Junctions independent of the α-catenin-vinculin module. Oldenburg J, et al. Sci Rep, 2015 Nov 27. PMID 26611125, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. VASP, zyxin and TES are tension-dependent members of focal adherens junctions independent of the alpha-catenin-vinculin module.
    Title: VASP, zyxin and TES are tension-dependent members of Focal Adherens Junctions independent of the α-catenin-vinculin module.
  2. investigated the role of VASP during entry of herpes simplex viruses into epithelial MDCKII cells
    Title: Herpes simplex virus type 1 entry into epithelial MDCKII cells: role of VASP activities.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables profilin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in actin polymerization or depolymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neural tube closure IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of actin filament polymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein homotetramerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
vasodilator-stimulated phosphoprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003256.1 → NP_001003256.1  vasodilator-stimulated phosphoprotein

    See identical proteins and their annotated locations for NP_001003256.1

    Status: PROVISIONAL

    Source sequence(s)
    Z46388
    UniProtKB/Swiss-Prot
    P50551
    UniProtKB/TrEMBL
    A0A8C0M6S4, A0A8I3MWA4
    Related
    ENSCAFP00845007209.1, ENSCAFT00845009156.1
    Conserved Domains (3) summary
    cd01207
    Location:5 → 102
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
    pfam08776
    Location:346 → 381
    VASP_tetra; VASP tetramerisation domain
    cl27330
    Location:229 → 384
    FlhF; Flagellar biosynthesis GTPase FlhF [Cell motility]

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    110582754..110595760 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038653402.1 → XP_038509330.1  vasodilator-stimulated phosphoprotein isoform X3

    UniProtKB/TrEMBL
    A0A8C0M6S4, A0A8C0S0R8, A0A8I3MUF9, A0A8I3MWA4
    Related
    ENSCAFP00845007211.1, ENSCAFT00845009161.1
    Conserved Domains (4) summary
    PRK06995
    Location:229 → 385
    flhF; flagellar biosynthesis protein FlhF
    cd01207
    Location:5 → 102
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
    pfam08776
    Location:347 → 382
    VASP_tetra; VASP tetramerisation domain
    cd22185
    Location:222 → 248
    WH2_hVASP-like; Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) of human Vasodilator-stimulated phosphoprotein and related proteins

  2. XM_038653401.1 → XP_038509329.1  vasodilator-stimulated phosphoprotein isoform X2

    UniProtKB/TrEMBL
    A0A8C0M6S4, A0A8I3MWA4
    Conserved Domains (4) summary
    PRK06995
    Location:263 → 418
    flhF; flagellar biosynthesis protein FlhF
    cd01207
    Location:39 → 136
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
    pfam08776
    Location:380 → 415
    VASP_tetra; VASP tetramerisation domain
    cd22185
    Location:256 → 282
    WH2_hVASP-like; Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) of human Vasodilator-stimulated phosphoprotein and related proteins

  3. XM_038653400.1 → XP_038509328.1  vasodilator-stimulated phosphoprotein isoform X1

    UniProtKB/TrEMBL
    A0A8C0QGR9, A0A8I3MQ48
    Related
    ENSCAFP00845007213.1, ENSCAFT00845009165.1
    Conserved Domains (4) summary
    PRK06995
    Location:263 → 419
    flhF; flagellar biosynthesis protein FlhF
    cd01207
    Location:39 → 136
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
    pfam08776
    Location:381 → 416
    VASP_tetra; VASP tetramerisation domain
    cd22185
    Location:256 → 282
    WH2_hVASP-like; Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) of human Vasodilator-stimulated phosphoprotein and related proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    110258575..110271274 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    109892681..109905376 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    110762040..110774746 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    109534415..109547108 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P50551.3 GenPept UniProtKB/Swiss-Prot:P50551

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