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GNAQ G protein subunit alpha q [ Canis lupus familiaris (dog) ]

Gene ID: 403928, updated on 5-Mar-2024

Summary

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Official Symbol
GNAQprovided by VGNC
Official Full Name
G protein subunit alpha qprovided by VGNC
Primary source
VGNC:VGNC:41306
See related
Ensembl:ENSCAFG00845009564
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (81038541..81345574)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (81197285..81391732)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (81383410..81578003)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (80931602..81126112)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (80652980..80847487)

Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111096628 Neighboring gene uncharacterized LOC111096629 Neighboring gene uncharacterized LOC111096630 Neighboring gene uncharacterized LOC111096633 Neighboring gene G protein subunit alpha 14 Neighboring gene vacuolar protein sorting 13 homolog A Neighboring gene protein SET-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Modulation of Ca²+ activity in cardiomyocytes through caveolae-Gαq interactions. Guo Y, et al. Biophys J, 2011 Apr 6. PMID 21463572, Free PMC Article
  2. Specificity of G alpha q and G alpha 11 gene expression in platelets and erythrocytes. Expressions of cellular differentiation and species differences. Johnson GJ, et al. Biochem J, 1996 Sep 15. PMID 8836152, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G-protein beta/gamma-subunit complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl nucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipase C-activating dopamine receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of heterotrimeric G-protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
guanine nucleotide-binding protein G(q) subunit alpha
Names
G alpha q
guanine nucleotide binding protein (G protein), q polypeptide
guanine nucleotide-binding protein alpha-q

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003249.1 → NP_001003249.1  guanine nucleotide-binding protein G(q) subunit alpha

    See identical proteins and their annotated locations for NP_001003249.1

    Status: VALIDATED

    Source sequence(s)
    JAAUVH010000354, L76257
    UniProtKB/Swiss-Prot
    Q28294
    Related
    ENSCAFP00845013101.1, ENSCAFT00845016843.1
    Conserved Domains (1) summary
    cd00066
    Location:1 → 295
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051805.1 Reference ROS_Cfam_1.0

    Range
    81038541..81345574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038653399.1 → XP_038509327.1  guanine nucleotide-binding protein G(q) subunit alpha isoform X1

    UniProtKB/Swiss-Prot
    Q28294
    UniProtKB/TrEMBL
    A0A8C0LPJ6, A0A8C0M1E6
    Conserved Domains (1) summary
    cd00066
    Location:40 → 353
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049261.1 Alternate UMICH_Zoey_3.1

    Range
    80931602..81126112
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

    Range
    80652980..80847487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

    Range
    81383410..81578003
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    81197285..81391732
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q28294.2 GenPept UniProtKB/Swiss-Prot:Q28294

Gene LinkOut

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