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NRAS NRAS proto-oncogene, GTPase [ Canis lupus familiaris (dog) ]

Gene ID: 403872, updated on 5-Mar-2024

Summary

Official Symbol
NRASprovided by VGNC
Official Full Name
NRAS proto-oncogene, GTPaseprovided by VGNC
Primary source
VGNC:VGNC:43959
See related
Ensembl:ENSCAFG00845026380
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
N-RAS; rasp21
Orthologs
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Genomic context

See NRAS in Genome Data Viewer
Location:
chromosome: 17
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (53289080..53296149, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (52062320..52069399, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (52938741..52945813, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (52323232..52330285, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (52365409..52372486, complement)

Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106559931 Neighboring gene adenosine monophosphate deaminase 1 Neighboring gene cold shock domain containing E1 Neighboring gene uncharacterized LOC111090677

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GDP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
GTPase NRas
Names
neuroblastoma RAS viral oncogene homolog
NP_001273994.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001287065.1NP_001273994.1  GTPase NRas

    See identical proteins and their annotated locations for NP_001273994.1

    Status: VALIDATED

    Source sequence(s)
    JAAUVH010000359
    UniProtKB/TrEMBL
    A0A8C0S2X6, A0A8C0S329, A0A8I3PSP7, A0A8I3PXY1
    Related
    ENSCAFP00845036549.1, ENSCAFT00845046556.1
    Conserved Domains (1) summary
    cd04138
    Location:3164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051821.1 Reference ROS_Cfam_1.0

    Range
    53289080..53296149 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049277.1 Alternate UMICH_Zoey_3.1

    Range
    52323232..52330285 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

    Range
    52365409..52372486 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

    Range
    52938741..52945813 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    52062320..52069399 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)