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ADRA1A adrenoceptor alpha 1A [ Canis lupus familiaris (dog) ]

Gene ID: 403866, updated on 5-Mar-2024

Summary

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Official Symbol
ADRA1Aprovided by VGNC
Official Full Name
adrenoceptor alpha 1Aprovided by VGNC
Primary source
VGNC:VGNC:37672
See related
Ensembl:ENSCAFG00845012931
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
ADRA1C; ALPHA-1A
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 25
Exon count:
5
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (30890909..31000565)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (31281657..31383233)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (30864630..30965891)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (30825262..30929065)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (30697626..30799475)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L7a-like Neighboring gene uncharacterized LOC119865849 Neighboring gene uncharacterized LOC111092295 Neighboring gene uncharacterized LOC111092296 Neighboring gene dihydropyrimidinase like 2 Neighboring gene PNMA family member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An alpha(1A)/alpha(1L)-adrenoceptor mediates contraction of canine subcutaneous resistance arteries. Argyle SA, et al. J Pharmacol Exp Ther, 2000 Nov. PMID 11046098

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alpha1-adrenergic receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cardiac muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of vasoconstriction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-1A adrenergic receptor
Names
adrenergic, alpha-1A-, receptor
alpha-1A adrenoceptor
alpha-1A adrenoreceptor
alpha-1C adrenergic receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195843.1 → NP_001182772.1  alpha-1A adrenergic receptor

    See identical proteins and their annotated locations for NP_001182772.1

    Status: PROVISIONAL

    Source sequence(s)
    JAAUVH010000302
    UniProtKB/TrEMBL
    A0A8C0T458, A0A8I3NK63, A0A8I3RZS8, A0A8P0P9R4
    Conserved Domains (1) summary
    cd15325
    Location:27 → 337
    7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    30890909..31000565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038434533.1 → XP_038290461.1  alpha-1A adrenergic receptor isoform X4

    UniProtKB/Swiss-Prot
    O77621
    Conserved Domains (2) summary
    cd14964
    Location:28 → 54
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:27 → 306
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_038434531.1 → XP_038290459.1  alpha-1A adrenergic receptor isoform X2

    UniProtKB/TrEMBL
    A0A8I3RZS8, A0A8P0P9R4
    Conserved Domains (1) summary
    cd15325
    Location:27 → 337
    7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038434532.1 → XP_038290460.1  alpha-1A adrenergic receptor isoform X3

    UniProtKB/TrEMBL
    A0A8C0T414, A0A8I3NE97, A0A8I3RZS8, A0A8P0P9R4
    Related
    ENSCAFP00845018063.1, ENSCAFT00845023039.1
    Conserved Domains (1) summary
    cd15325
    Location:27 → 337
    7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_038434528.1 → XP_038290456.1  alpha-1A adrenergic receptor isoform X1

    UniProtKB/TrEMBL
    A0A8C0T458, A0A8I3NK63, A0A8I3RZS8, A0A8P0P9R4
    Related
    ENSCAFP00845018036.1, ENSCAFT00845023005.1
    Conserved Domains (1) summary
    cd15325
    Location:27 → 337
    7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

  5. XM_038434529.1 → XP_038290457.1  alpha-1A adrenergic receptor isoform X1

    UniProtKB/TrEMBL
    A0A8C0T458, A0A8I3NK63, A0A8I3RZS8, A0A8P0P9R4
    Conserved Domains (1) summary
    cd15325
    Location:27 → 337
    7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

  6. XM_038434530.1 → XP_038290458.1  alpha-1A adrenergic receptor isoform X1

    UniProtKB/TrEMBL
    A0A8C0T458, A0A8I3NK63, A0A8I3RZS8, A0A8P0P9R4
    Conserved Domains (1) summary
    cd15325
    Location:27 → 337
    7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. XR_005301335.1 RNA Sequence

  2. XR_005301336.1 RNA Sequence

    Related
    ENSCAFT00845023091.1

  3. XR_005301334.1 RNA Sequence

  4. XR_005301333.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    30825262..30929065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    30697626..30799475
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    30864630..30965891
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    31281657..31383233
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O77621.1 GenPept UniProtKB/Swiss-Prot:O77621

Gene LinkOut

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