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CHRM2 cholinergic receptor muscarinic 2 [ Canis lupus familiaris (dog) ]

Gene ID: 403858, updated on 5-Mar-2024

Summary

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Official Symbol
CHRM2provided by VGNC
Official Full Name
cholinergic receptor muscarinic 2provided by VGNC
Primary source
VGNC:VGNC:39232
See related
Ensembl:ENSCAFG00845008775
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 16
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 16 NC_051820.1 (11480293..11633043, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 16 NC_006598.4 (12526682..12678872, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 16 NC_049237.1 (11179681..11325556, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 16 NC_049276.1 (11939562..12085418, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 16 NC_049757.1 (11039665..11185727, complement)

Chromosome 16 - NC_051820.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111090242 Neighboring gene diacylglycerol kinase iota Neighboring gene uncharacterized LOC111090243 Neighboring gene pleiotrophin Neighboring gene WAS/WASL-interacting protein family member 3-like Neighboring gene microRNA mir-490 Neighboring gene protein Shroom3-like Neighboring gene uncharacterized LOC111090156

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The M3 receptor-mediated K(+) current (IKM3), a G(q) protein-coupled K(+) channel. Shi H, et al. J Biol Chem, 2004 May 21. PMID 15140874

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled acetylcholine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of heart contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
muscarinic acetylcholine receptor M2
Names
muscarinic acetylcholine receptor m2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051820.1 Reference ROS_Cfam_1.0

    Range
    11480293..11633043 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038689146.1 → XP_038545074.1  muscarinic acetylcholine receptor M2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LTT6, A0A8C0MWL4, A0A8I3N4M6, A0A8I3RUS6, A0A8P0PP20
    Related
    ENSCAFP00845011964.1, ENSCAFT00845015405.1
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038689145.1 → XP_038545073.1  muscarinic acetylcholine receptor M2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LTT6, A0A8C0MWL4, A0A8I3N4M6, A0A8I3RUS6, A0A8P0PP20
    Related
    ENSCAFP00845012005.1, ENSCAFT00845015458.1
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038689147.1 → XP_038545075.1  muscarinic acetylcholine receptor M2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LTT6, A0A8C0MWL4, A0A8I3N4M6, A0A8I3RUS6, A0A8P0PP20
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049276.1 Alternate UMICH_Zoey_3.1

    Range
    11939562..12085418 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038497129.1 → XP_038353057.1  muscarinic acetylcholine receptor M2 isoform X1

    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038497128.1 → XP_038353056.1  muscarinic acetylcholine receptor M2 isoform X2

  3. XM_038497130.1 → XP_038353058.1  muscarinic acetylcholine receptor M2 isoform X1

    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049757.1 Alternate UNSW_CanFamBas_1.0

    Range
    11039665..11185727 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038623437.1 → XP_038479365.1  muscarinic acetylcholine receptor M2 isoform X1

    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038623436.1 → XP_038479364.1  muscarinic acetylcholine receptor M2 isoform X1

    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038623438.1 → XP_038479366.1  muscarinic acetylcholine receptor M2 isoform X1

    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049237.1 Alternate UU_Cfam_GSD_1.0

    Range
    11179681..11325556 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038559445.1 → XP_038415373.1  muscarinic acetylcholine receptor M2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LTT6, A0A8C0MWL4, A0A8I3N4M6, A0A8I3RUS6, A0A8P0PP20
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038559444.1 → XP_038415372.1  muscarinic acetylcholine receptor M2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LTT6, A0A8C0MWL4, A0A8I3N4M6, A0A8I3RUS6, A0A8P0PP20
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038559446.1 → XP_038415374.1  muscarinic acetylcholine receptor M2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LTT6, A0A8C0MWL4, A0A8I3N4M6, A0A8I3RUS6, A0A8P0PP20
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006598.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    12526682..12678872 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005629578.4 → XP_005629635.1  muscarinic acetylcholine receptor M2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LTT6, A0A8C0MWL4, A0A8I3N4M6, A0A8I3RUS6, A0A8P0PP20
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038452644.1 → XP_038308572.1  muscarinic acetylcholine receptor M2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LTT6, A0A8C0MWL4, A0A8I3N4M6, A0A8I3RUS6, A0A8P0PP20
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_038452645.1 → XP_038308573.1  muscarinic acetylcholine receptor M2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LTT6, A0A8C0MWL4, A0A8I3N4M6, A0A8I3RUS6, A0A8P0PP20
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein
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