IL2RG interleukin 2 receptor subunit gamma [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: IL2RGprovided by VGNC
Official Full Name: interleukin 2 receptor subunit gammaprovided by VGNC
Primary source: VGNC:VGNC:41979
See related: Ensembl:ENSCAFG00845017057
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: X

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	X	NC_051843.1 (56449759..56453658, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	X	NC_006621.4 (46308162..46311760, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	X	NC_049260.1 (55676806..55680404, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	X	NC_049299.1 (54418234..54421830, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	X	NC_049780.1 (55749655..55753253, complement)

Chromosome X - NC_051843.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The present study has characterized the expression of the IL-2R beta and gamma chains and the ligand IL-2 in canine cutaneous mast cell tumours
Title: All subunits of the interleukin-2 receptor are expressed by canine cutaneous mast cell tumours.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cytokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cytokine receptor common subunit gamma

Names: IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; gammaC; interleukin 2 receptor gamma chain; interleukin 2 receptor, gamma (severe combined immunodeficiency); p64

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003201.1 → NP_001003201.1 cytokine receptor common subunit gamma precursor

See identical proteins and their annotated locations for NP_001003201.1

Status: PROVISIONAL

Source sequence(s)

U04361

UniProtKB/Swiss-Prot

P40321

UniProtKB/TrEMBL

A0A8C0L3N9, A0A8P0NSC9

Related

ENSCAFP00845023718.1, ENSCAFT00845030246.1

Conserved Domains (2) summary

cd00063
Location:154 → 246

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cl21522
Location:59 → 151

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051843.1 Reference ROS_Cfam_1.0

Range

56449759..56453658 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038448818.1 → XP_038304746.1 cytokine receptor common subunit gamma isoform X1

UniProtKB/TrEMBL

A0A8P0NSC9

Conserved Domains (2) summary

cd00063
Location:162 → 254

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cl21522
Location:67 → 159

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...