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AGTR1 angiotensin II receptor type 1 [ Canis lupus familiaris (dog) ]

Gene ID: 403836, updated on 5-Mar-2024

Summary

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Official Symbol
AGTR1provided by VGNC
Official Full Name
angiotensin II receptor type 1provided by VGNC
Primary source
VGNC:VGNC:37720
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
AT1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 23
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 23 NC_051827.1 (44190631..44238133)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 23 NC_006605.4 (43434074..43481582)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 23 NC_049244.1 (44086806..44134323)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 23 NC_049283.1 (43779664..43827179)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 23 NC_049764.1 (43832799..43880312)

Chromosome 23 - NC_051827.1Genomic Context describing neighboring genes Neighboring gene ATP synthase subunit d, mitochondrial-like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC119865416 Neighboring gene carboxypeptidase B1 Neighboring gene carboxypeptidase A3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Coronary arteriolar vasoconstriction to angiotensin II is augmented in prediabetic metabolic syndrome via activation of AT1 receptors. Zhang C, et al. Am J Physiol Heart Circ Physiol, 2005 May. PMID 15653764
  2. Molecular cloning of the canine angiotensin II receptor. An AT1-like receptor with reduced affinity for DuP753. Burns L, et al. FEBS Lett, 1994 Apr 25. PMID 8168620
  3. [On angiotensin II receptor distribution after myocardial infarction in dogs]. Qu XF, et al. Zhonghua Xin Xue Guan Bing Za Zhi, 2009 Apr. PMID 19791474
  4. Local stress, not systemic factors, regulate gene expression of the cardiac renin-angiotensin system in vivo: a comprehensive study of all its components in the dog. Lee YA, et al. Proc Natl Acad Sci U S A, 1996 Oct 1. PMID 8855304, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables angiotensin type II receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of vasoconstriction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
type-1 angiotensin II receptor
Names
Angiotensin II type-1 receptor
Type-1 angiotensin II receptor
angiotensin II type 1 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051827.1 Reference ROS_Cfam_1.0

    Range
    44190631..44238133
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038432622.1 → XP_038288550.1  type-1 angiotensin II receptor

    UniProtKB/Swiss-Prot
    P43240
    UniProtKB/TrEMBL
    A0A8C0L3S2
    Conserved Domains (1) summary
    cd15192
    Location:29 → 313
    7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038432621.1 → XP_038288549.1  type-1 angiotensin II receptor

    UniProtKB/Swiss-Prot
    P43240
    UniProtKB/TrEMBL
    A0A8C0L3S2
    Conserved Domains (1) summary
    cd15192
    Location:29 → 313
    7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049283.1 Alternate UMICH_Zoey_3.1

    Range
    43779664..43827179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038507918.1 → XP_038363846.1  type-1 angiotensin II receptor

    Conserved Domains (1) summary
    cd15192
    Location:29 → 313
    7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038507917.1 → XP_038363845.1  type-1 angiotensin II receptor

    Conserved Domains (1) summary
    cd15192
    Location:29 → 313
    7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049764.1 Alternate UNSW_CanFamBas_1.0

    Range
    43832799..43880312
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038635352.1 → XP_038491280.1  type-1 angiotensin II receptor

    Conserved Domains (1) summary
    cd15192
    Location:29 → 313
    7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038635351.1 → XP_038491279.1  type-1 angiotensin II receptor

    Conserved Domains (1) summary
    cd15192
    Location:29 → 313
    7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049244.1 Alternate UU_Cfam_GSD_1.0

    Range
    44086806..44134323
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038571160.1 → XP_038427088.1  type-1 angiotensin II receptor

    UniProtKB/Swiss-Prot
    P43240
    UniProtKB/TrEMBL
    A0A8C0L3S2
    Conserved Domains (1) summary
    cd15192
    Location:29 → 313
    7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_038571159.1 → XP_038427087.1  type-1 angiotensin II receptor

    UniProtKB/Swiss-Prot
    P43240
    UniProtKB/TrEMBL
    A0A8C0L3S2
    Conserved Domains (1) summary
    cd15192
    Location:29 → 313
    7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006605.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    43434074..43481582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005634552.4 → XP_005634609.1  type-1 angiotensin II receptor

    See identical proteins and their annotated locations for XP_005634609.1

    UniProtKB/Swiss-Prot
    P43240
    UniProtKB/TrEMBL
    A0A8C0L3S2
    Conserved Domains (1) summary
    cd15192
    Location:29 → 313
    7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_003433161.5 → XP_003433209.1  type-1 angiotensin II receptor

    See identical proteins and their annotated locations for XP_003433209.1

    UniProtKB/Swiss-Prot
    P43240
    UniProtKB/TrEMBL
    A0A8C0L3S2
    Conserved Domains (1) summary
    cd15192
    Location:29 → 313
    7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P43240.1 GenPept UniProtKB/Swiss-Prot:P43240

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