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FLT1 fms related receptor tyrosine kinase 1 [ Canis lupus familiaris (dog) ]

Gene ID: 403727, updated on 5-Mar-2024

Summary

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Official Symbol
FLT1provided by VGNC
Official Full Name
fms related receptor tyrosine kinase 1provided by VGNC
Primary source
VGNC:VGNC:40907
See related
Ensembl:ENSCAFG00845023188
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
VEGFR-1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 25
Exon count:
33
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (11359770..11538425)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (11295043..11473288)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (11290416..11468726)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (11255914..11434257)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (11248371..11426845)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111092297 Neighboring gene small nucleolar RNA U3 Neighboring gene poly(A) specific ribonuclease subunit PAN3 Neighboring gene fms related receptor tyrosine kinase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression of vascular endothelial growth factor receptor-1 and -2 in normal and diseased canine eyes. Binder DR, et al. Vet Ophthalmol, 2012 Jul. PMID 22117605
  2. Distribution of VEGF and flt-1 in the normal dog tissues. Uchida N, et al. J Vet Med Sci, 2008 Nov. PMID 19057151
  3. Expression of vascular endothelial growth factor and its receptors in canine lymphoma. Wolfesberger B, et al. J Comp Pathol, 2007 Jul. PMID 17467003
  4. Expression of vascular endothelial growth factor, basic fibroblast growth factor, and their receptors (flt-1, flk-1, and flg-1) in canine vascular tumors. Yonemaru K, et al. Vet Pathol, 2006 Nov. PMID 17099154

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The results of this study suggest a role for VEGF receptors in both physiologic and pathologic angiogenesis in canine ocular tissue.
    Title: Expression of vascular endothelial growth factor receptor-1 and -2 in normal and diseased canine eyes.
  2. VEGF and flt-1 are closely associated in canine, as in human tissues, and quantifying their mRNAs might be helpful in evaluating angiogenesis.
    Title: Distribution of VEGF and flt-1 in the normal dog tissues.
  3. VEGFR-1 was expressed by variable numbers of neoplastic cells in 54% of canine lymphoma specimens. VEGFR-1 was also expressed by macrophages, plasma cells, reticulum cells, and vascular endothelial cells.
    Title: Expression of vascular endothelial growth factor and its receptors in canine lymphoma.
  4. Expression of vascular endothelial growth factor (VEGF), its receptors (flt-1 and flk-1), and basic fibroblast growth factor (bFGF) in canine hemangiosarcoma (HSA) and hemangiomas was investigated by immunohistochemical analysis.
    Title: Expression of vascular endothelial growth factor, basic fibroblast growth factor, and their receptors (flt-1, flk-1, and flg-1) in canine vascular tumors.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables vascular endothelial growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vascular endothelial growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
vascular endothelial growth factor receptor 1
Names
ascular endothelial growth factor/vascular permeability factor receptor
fms related tyrosine kinase 1
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
XP_005635561.1
XP_022265451.1
XP_022265452.1
XP_038290893.1
XP_038290894.1
XP_038290895.1
XP_038290896.1
XP_038290897.1
XP_038314211.1
XP_038365878.1
XP_038365879.1
XP_038365880.1
XP_038365881.1
XP_038365882.1
XP_038429308.1
XP_038429309.1
XP_038429310.1
XP_038429311.1
XP_038429312.1
XP_038429313.1
XP_038493602.1
XP_038493603.1
XP_038493604.1
XP_038493605.1
XP_038493606.1
XP_038493607.1
XP_534520.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    11359770..11538425
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038434966.1 → XP_038290894.1  vascular endothelial growth factor receptor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NYS8, A0A8C0T189, A0A8I3PN58
    Related
    ENSCAFP00845032381.1, ENSCAFT00845041302.1
    Conserved Domains (7) summary
    smart00409
    Location:568 → 640
    IG; Immunoglobulin
    smart00410
    Location:143 → 219
    IG_like; Immunoglobulin like
    pfam07679
    Location:661 → 748
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:427 → 539
    Ig_3; Immunoglobulin domain
    cd00096
    Location:333 → 337
    Ig; Ig strand A [structural motif]
    cl11960
    Location:333 → 424
    Ig; Immunoglobulin domain
    cl21453
    Location:819 → 1157
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038434965.1 → XP_038290893.1  vascular endothelial growth factor receptor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0T189
    Conserved Domains (7) summary
    smart00409
    Location:568 → 640
    IG; Immunoglobulin
    smart00410
    Location:143 → 219
    IG_like; Immunoglobulin like
    pfam07679
    Location:661 → 748
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:427 → 539
    Ig_3; Immunoglobulin domain
    cd00096
    Location:333 → 337
    Ig; Ig strand A [structural motif]
    cl11960
    Location:333 → 424
    Ig; Immunoglobulin domain
    cl21453
    Location:819 → 1157
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038434968.1 → XP_038290896.1  vascular endothelial growth factor receptor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0T393, A0A8I3PIN5
    Related
    ENSCAFP00845032551.1, ENSCAFT00845041521.1
    Conserved Domains (7) summary
    smart00409
    Location:431 → 503
    IG; Immunoglobulin
    smart00410
    Location:6 → 82
    IG_like; Immunoglobulin like
    pfam07679
    Location:524 → 611
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:290 → 402
    Ig_3; Immunoglobulin domain
    cd00096
    Location:196 → 200
    Ig; Ig strand A [structural motif]
    cl11960
    Location:196 → 287
    Ig; Immunoglobulin domain
    cl21453
    Location:682 → 1020
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038434969.1 → XP_038290897.1  vascular endothelial growth factor receptor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0T393, A0A8I3PIN5
    Conserved Domains (7) summary
    smart00409
    Location:431 → 503
    IG; Immunoglobulin
    smart00410
    Location:6 → 82
    IG_like; Immunoglobulin like
    pfam07679
    Location:524 → 611
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:290 → 402
    Ig_3; Immunoglobulin domain
    cd00096
    Location:196 → 200
    Ig; Ig strand A [structural motif]
    cl11960
    Location:196 → 287
    Ig; Immunoglobulin domain
    cl21453
    Location:682 → 1020
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038434967.1 → XP_038290895.1  vascular endothelial growth factor receptor 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0T393, A0A8I3PIN5
    Conserved Domains (7) summary
    smart00409
    Location:476 → 548
    IG; Immunoglobulin
    smart00410
    Location:51 → 127
    IG_like; Immunoglobulin like
    pfam07679
    Location:569 → 656
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:335 → 447
    Ig_3; Immunoglobulin domain
    cd00096
    Location:241 → 245
    Ig; Ig strand A [structural motif]
    cl11960
    Location:241 → 332
    Ig; Immunoglobulin domain
    cl21453
    Location:727 → 1065
    PKc_like; Protein Kinases, catalytic domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    11255914..11434257
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038509951.1 → XP_038365879.1  vascular endothelial growth factor receptor 1 isoform X2

    Conserved Domains (7) summary
    smart00409
    Location:568 → 640
    IG; Immunoglobulin
    smart00410
    Location:143 → 219
    IG_like; Immunoglobulin like
    pfam07679
    Location:661 → 748
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:427 → 539
    Ig_3; Immunoglobulin domain
    cd00096
    Location:333 → 337
    Ig; Ig strand A [structural motif]
    cl11960
    Location:333 → 424
    Ig; Immunoglobulin domain
    cl21453
    Location:819 → 1157
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038509950.1 → XP_038365878.1  vascular endothelial growth factor receptor 1 isoform X1

    Conserved Domains (7) summary
    smart00409
    Location:568 → 640
    IG; Immunoglobulin
    smart00410
    Location:143 → 219
    IG_like; Immunoglobulin like
    pfam07679
    Location:661 → 748
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:427 → 539
    Ig_3; Immunoglobulin domain
    cd00096
    Location:333 → 337
    Ig; Ig strand A [structural motif]
    cl11960
    Location:333 → 424
    Ig; Immunoglobulin domain
    cl21453
    Location:819 → 1157
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038509953.1 → XP_038365881.1  vascular endothelial growth factor receptor 1 isoform X4

    Conserved Domains (7) summary
    smart00409
    Location:431 → 503
    IG; Immunoglobulin
    smart00410
    Location:6 → 82
    IG_like; Immunoglobulin like
    pfam07679
    Location:524 → 611
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:290 → 402
    Ig_3; Immunoglobulin domain
    cd00096
    Location:196 → 200
    Ig; Ig strand A [structural motif]
    cl11960
    Location:196 → 287
    Ig; Immunoglobulin domain
    cl21453
    Location:682 → 1020
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038509954.1 → XP_038365882.1  vascular endothelial growth factor receptor 1 isoform X4

    Conserved Domains (7) summary
    smart00409
    Location:431 → 503
    IG; Immunoglobulin
    smart00410
    Location:6 → 82
    IG_like; Immunoglobulin like
    pfam07679
    Location:524 → 611
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:290 → 402
    Ig_3; Immunoglobulin domain
    cd00096
    Location:196 → 200
    Ig; Ig strand A [structural motif]
    cl11960
    Location:196 → 287
    Ig; Immunoglobulin domain
    cl21453
    Location:682 → 1020
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038509952.1 → XP_038365880.1  vascular endothelial growth factor receptor 1 isoform X3

    Conserved Domains (7) summary
    smart00409
    Location:476 → 548
    IG; Immunoglobulin
    smart00410
    Location:51 → 127
    IG_like; Immunoglobulin like
    pfam07679
    Location:569 → 656
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:335 → 447
    Ig_3; Immunoglobulin domain
    cd00096
    Location:241 → 245
    Ig; Ig strand A [structural motif]
    cl11960
    Location:241 → 332
    Ig; Immunoglobulin domain
    cl21453
    Location:727 → 1065
    PKc_like; Protein Kinases, catalytic domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    11248371..11426845
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038637675.1 → XP_038493603.1  vascular endothelial growth factor receptor 1 isoform X2

    Conserved Domains (7) summary
    smart00409
    Location:568 → 640
    IG; Immunoglobulin
    smart00410
    Location:143 → 219
    IG_like; Immunoglobulin like
    pfam07679
    Location:661 → 748
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:427 → 539
    Ig_3; Immunoglobulin domain
    cd00096
    Location:333 → 337
    Ig; Ig strand A [structural motif]
    cl11960
    Location:333 → 424
    Ig; Immunoglobulin domain
    cl21453
    Location:819 → 1157
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038637674.1 → XP_038493602.1  vascular endothelial growth factor receptor 1 isoform X1

    Conserved Domains (7) summary
    smart00409
    Location:568 → 640
    IG; Immunoglobulin
    smart00410
    Location:143 → 219
    IG_like; Immunoglobulin like
    pfam07679
    Location:661 → 748
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:427 → 539
    Ig_3; Immunoglobulin domain
    cd00096
    Location:333 → 337
    Ig; Ig strand A [structural motif]
    cl11960
    Location:333 → 424
    Ig; Immunoglobulin domain
    cl21453
    Location:819 → 1157
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038637679.1 → XP_038493607.1  vascular endothelial growth factor receptor 1 isoform X4

    Conserved Domains (7) summary
    smart00409
    Location:431 → 503
    IG; Immunoglobulin
    smart00410
    Location:6 → 82
    IG_like; Immunoglobulin like
    pfam07679
    Location:524 → 611
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:290 → 402
    Ig_3; Immunoglobulin domain
    cd00096
    Location:196 → 200
    Ig; Ig strand A [structural motif]
    cl11960
    Location:196 → 287
    Ig; Immunoglobulin domain
    cl21453
    Location:682 → 1020
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038637677.1 → XP_038493605.1  vascular endothelial growth factor receptor 1 isoform X4

    Conserved Domains (7) summary
    smart00409
    Location:431 → 503
    IG; Immunoglobulin
    smart00410
    Location:6 → 82
    IG_like; Immunoglobulin like
    pfam07679
    Location:524 → 611
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:290 → 402
    Ig_3; Immunoglobulin domain
    cd00096
    Location:196 → 200
    Ig; Ig strand A [structural motif]
    cl11960
    Location:196 → 287
    Ig; Immunoglobulin domain
    cl21453
    Location:682 → 1020
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038637678.1 → XP_038493606.1  vascular endothelial growth factor receptor 1 isoform X4

    Conserved Domains (7) summary
    smart00409
    Location:431 → 503
    IG; Immunoglobulin
    smart00410
    Location:6 → 82
    IG_like; Immunoglobulin like
    pfam07679
    Location:524 → 611
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:290 → 402
    Ig_3; Immunoglobulin domain
    cd00096
    Location:196 → 200
    Ig; Ig strand A [structural motif]
    cl11960
    Location:196 → 287
    Ig; Immunoglobulin domain
    cl21453
    Location:682 → 1020
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038637676.1 → XP_038493604.1  vascular endothelial growth factor receptor 1 isoform X3

    Conserved Domains (7) summary
    smart00409
    Location:476 → 548
    IG; Immunoglobulin
    smart00410
    Location:51 → 127
    IG_like; Immunoglobulin like
    pfam07679
    Location:569 → 656
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:335 → 447
    Ig_3; Immunoglobulin domain
    cd00096
    Location:241 → 245
    Ig; Ig strand A [structural motif]
    cl11960
    Location:241 → 332
    Ig; Immunoglobulin domain
    cl21453
    Location:727 → 1065
    PKc_like; Protein Kinases, catalytic domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    11290416..11468726
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038573381.1 → XP_038429309.1  vascular endothelial growth factor receptor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NYS8, A0A8C0T189, A0A8I3PN58
    Conserved Domains (7) summary
    smart00409
    Location:568 → 640
    IG; Immunoglobulin
    smart00410
    Location:143 → 219
    IG_like; Immunoglobulin like
    pfam07679
    Location:661 → 748
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:427 → 539
    Ig_3; Immunoglobulin domain
    cd00096
    Location:333 → 337
    Ig; Ig strand A [structural motif]
    cl11960
    Location:333 → 424
    Ig; Immunoglobulin domain
    cl21453
    Location:819 → 1157
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038573380.1 → XP_038429308.1  vascular endothelial growth factor receptor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0T189
    Conserved Domains (7) summary
    smart00409
    Location:568 → 640
    IG; Immunoglobulin
    smart00410
    Location:143 → 219
    IG_like; Immunoglobulin like
    pfam07679
    Location:661 → 748
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:427 → 539
    Ig_3; Immunoglobulin domain
    cd00096
    Location:333 → 337
    Ig; Ig strand A [structural motif]
    cl11960
    Location:333 → 424
    Ig; Immunoglobulin domain
    cl21453
    Location:819 → 1157
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038573385.1 → XP_038429313.1  vascular endothelial growth factor receptor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0T393, A0A8I3PIN5
    Conserved Domains (7) summary
    smart00409
    Location:431 → 503
    IG; Immunoglobulin
    smart00410
    Location:6 → 82
    IG_like; Immunoglobulin like
    pfam07679
    Location:524 → 611
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:290 → 402
    Ig_3; Immunoglobulin domain
    cd00096
    Location:196 → 200
    Ig; Ig strand A [structural motif]
    cl11960
    Location:196 → 287
    Ig; Immunoglobulin domain
    cl21453
    Location:682 → 1020
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038573383.1 → XP_038429311.1  vascular endothelial growth factor receptor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0T393, A0A8I3PIN5
    Conserved Domains (7) summary
    smart00409
    Location:431 → 503
    IG; Immunoglobulin
    smart00410
    Location:6 → 82
    IG_like; Immunoglobulin like
    pfam07679
    Location:524 → 611
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:290 → 402
    Ig_3; Immunoglobulin domain
    cd00096
    Location:196 → 200
    Ig; Ig strand A [structural motif]
    cl11960
    Location:196 → 287
    Ig; Immunoglobulin domain
    cl21453
    Location:682 → 1020
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038573384.1 → XP_038429312.1  vascular endothelial growth factor receptor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0T393, A0A8I3PIN5
    Conserved Domains (7) summary
    smart00409
    Location:431 → 503
    IG; Immunoglobulin
    smart00410
    Location:6 → 82
    IG_like; Immunoglobulin like
    pfam07679
    Location:524 → 611
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:290 → 402
    Ig_3; Immunoglobulin domain
    cd00096
    Location:196 → 200
    Ig; Ig strand A [structural motif]
    cl11960
    Location:196 → 287
    Ig; Immunoglobulin domain
    cl21453
    Location:682 → 1020
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038573382.1 → XP_038429310.1  vascular endothelial growth factor receptor 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0T393, A0A8I3PIN5
    Conserved Domains (7) summary
    smart00409
    Location:476 → 548
    IG; Immunoglobulin
    smart00410
    Location:51 → 127
    IG_like; Immunoglobulin like
    pfam07679
    Location:569 → 656
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:335 → 447
    Ig_3; Immunoglobulin domain
    cd00096
    Location:241 → 245
    Ig; Ig strand A [structural motif]
    cl11960
    Location:241 → 332
    Ig; Immunoglobulin domain
    cl21453
    Location:727 → 1065
    PKc_like; Protein Kinases, catalytic domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    11295043..11473288
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_534520.6 → XP_534520.2  vascular endothelial growth factor receptor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0NYS8, A0A8C0T189, A0A8I3PN58
    Conserved Domains (7) summary
    smart00409
    Location:568 → 640
    IG; Immunoglobulin
    smart00410
    Location:143 → 219
    IG_like; Immunoglobulin like
    pfam07679
    Location:661 → 748
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:427 → 539
    Ig_3; Immunoglobulin domain
    cd00096
    Location:333 → 337
    Ig; Ig strand A [structural motif]
    cl11960
    Location:333 → 424
    Ig; Immunoglobulin domain
    cl21453
    Location:819 → 1157
    PKc_like; Protein Kinases, catalytic domain

  2. XM_005635504.4 → XP_005635561.1  vascular endothelial growth factor receptor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C0T189
    Conserved Domains (7) summary
    smart00409
    Location:568 → 640
    IG; Immunoglobulin
    smart00410
    Location:143 → 219
    IG_like; Immunoglobulin like
    pfam07679
    Location:661 → 748
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:427 → 539
    Ig_3; Immunoglobulin domain
    cd00096
    Location:333 → 337
    Ig; Ig strand A [structural motif]
    cl11960
    Location:333 → 424
    Ig; Immunoglobulin domain
    cl21453
    Location:819 → 1157
    PKc_like; Protein Kinases, catalytic domain

  3. XM_022409744.2 → XP_022265452.1  vascular endothelial growth factor receptor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0T393, A0A8I3PIN5
    Conserved Domains (7) summary
    smart00409
    Location:431 → 503
    IG; Immunoglobulin
    smart00410
    Location:6 → 82
    IG_like; Immunoglobulin like
    pfam07679
    Location:524 → 611
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:290 → 402
    Ig_3; Immunoglobulin domain
    cd00096
    Location:196 → 200
    Ig; Ig strand A [structural motif]
    cl11960
    Location:196 → 287
    Ig; Immunoglobulin domain
    cl21453
    Location:682 → 1020
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038458283.1 → XP_038314211.1  vascular endothelial growth factor receptor 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C0T393, A0A8I3PIN5
    Conserved Domains (7) summary
    smart00409
    Location:431 → 503
    IG; Immunoglobulin
    smart00410
    Location:6 → 82
    IG_like; Immunoglobulin like
    pfam07679
    Location:524 → 611
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:290 → 402
    Ig_3; Immunoglobulin domain
    cd00096
    Location:196 → 200
    Ig; Ig strand A [structural motif]
    cl11960
    Location:196 → 287
    Ig; Immunoglobulin domain
    cl21453
    Location:682 → 1020
    PKc_like; Protein Kinases, catalytic domain

  5. XM_022409743.2 → XP_022265451.1  vascular endothelial growth factor receptor 1 isoform X3

    UniProtKB/TrEMBL
    A0A8C0T393, A0A8I3PIN5
    Conserved Domains (7) summary
    smart00409
    Location:476 → 548
    IG; Immunoglobulin
    smart00410
    Location:51 → 127
    IG_like; Immunoglobulin like
    pfam07679
    Location:569 → 656
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:335 → 447
    Ig_3; Immunoglobulin domain
    cd00096
    Location:241 → 245
    Ig; Ig strand A [structural motif]
    cl11960
    Location:241 → 332
    Ig; Immunoglobulin domain
    cl21453
    Location:727 → 1065
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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