RHOB ras homolog family member B [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: RHOBprovided by VGNC
Official Full Name: ras homolog family member Bprovided by VGNC
Primary source: VGNC:VGNC:45555
See related: Ensembl:ENSCAFG00845019784
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: RHO
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	17	NC_051821.1 (15590936..15592006)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	17	NC_006599.4 (15403411..15404475)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	17	NC_049238.1 (15483858..15484931)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	17	NC_049277.1 (15444980..15446038)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	17	NC_049758.1 (15451597..15452660)

Chromosome 17 - NC_051821.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

RhoB is localized, in part, to early endosomes where it regulates receptor egress through the early endocytic system
Title: RhoB-dependent modulation of postendocytic traffic in polarized Madin-Darby canine kidney cells.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in small GTPase-mediated signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: rho-related GTP-binding protein RhoB

Names: ras homolog gene family, member B; ras-related rho protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001287052.2 → NP_001273981.2 rho-related GTP-binding protein RhoB

Status: VALIDATED

Source sequence(s)

JAAUVH010000359

UniProtKB/TrEMBL

A0A8C0NFA9, A0A8I3P075, A0A8P0SRU0

Related

ENSCAFP00845027303.1, ENSCAFT00845034859.1

Conserved Domains (1) summary

cd01870
Location:5 → 179

RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC