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PDE1A phosphodiesterase 1A [ Canis lupus familiaris (dog) ]

Gene ID: 403652, updated on 5-Mar-2024

Summary

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Official Symbol
PDE1Aprovided by VGNC
Official Full Name
phosphodiesterase 1Aprovided by VGNC
Primary source
VGNC:VGNC:44348
See related
Ensembl:ENSCAFG00845015431
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 36
Exon count:
22
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 36 NC_051840.1 (25410014..25745454, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 36 NC_006618.4 (25212919..25448739, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 36 NC_049257.1 (25608455..25838496, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 36 NC_049296.1 (25542676..25772033, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 36 NC_049777.1 (25472278..25701927, complement)

Chromosome 36 - NC_051840.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106558299 Neighboring gene ITPR interacting domain containing 2 Neighboring gene uncharacterized LOC102155256 Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 1C Neighboring gene small nucleolar RNA SNORD22 Neighboring gene uncharacterized LOC119867850 Neighboring gene uncharacterized LOC102155307 Neighboring gene uncharacterized LOC111094225 Neighboring gene tubulin beta chain-like Neighboring gene uncharacterized LOC119867851

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning of dog heart PDE1A - a first detailed characterization at the molecular level in this species. Clapham JC, et al. Gene, 2001 May 2. PMID 11368912

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-nucleotide phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Names
calmodulin-activated cyclic nucleotide phosphodiesterase
NP_001003091.1
XP_038302618.1
XP_038302619.1
XP_038302620.1
XP_038302621.1
XP_038302622.1
XP_038302623.1
XP_038302624.1
XP_038302625.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003091.1 → NP_001003091.1  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

    See identical proteins and their annotated locations for NP_001003091.1

    Status: PROVISIONAL

    Source sequence(s)
    AF252536
    UniProtKB/TrEMBL
    A0A8C0MTL8, A0A8P0NM13, Q95NB8
    Related
    ENSCAFP00845021820.1, ENSCAFT00845027724.1
    Conserved Domains (2) summary
    pfam00233
    Location:202 → 418
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08499
    Location:61 → 117
    PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051840.1 Reference ROS_Cfam_1.0

    Range
    25410014..25745454 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038446697.1 → XP_038302625.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8C0MTH3
    Conserved Domains (2) summary
    pfam00233
    Location:218 → 434
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08499
    Location:77 → 133
    PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

  2. XM_038446692.1 → XP_038302620.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8C0MTH3
    Conserved Domains (2) summary
    pfam00233
    Location:218 → 434
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08499
    Location:77 → 133
    PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

  3. XM_038446691.1 → XP_038302619.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8C0MTH3
    Conserved Domains (2) summary
    pfam00233
    Location:218 → 434
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08499
    Location:77 → 133
    PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

  4. XM_038446690.1 → XP_038302618.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8C0MTH3
    Conserved Domains (2) summary
    pfam00233
    Location:218 → 434
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08499
    Location:77 → 133
    PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

  5. XM_038446695.1 → XP_038302623.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X4

    UniProtKB/TrEMBL
    A0A8C0MTL8, A0A8P0NM13, Q95NB8
    Related
    ENSCAFP00845021775.1, ENSCAFT00845027666.1
    Conserved Domains (2) summary
    pfam00233
    Location:202 → 418
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08499
    Location:61 → 117
    PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

  6. XM_038446694.1 → XP_038302622.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X3

    UniProtKB/TrEMBL
    A0A8C0MTL8
    Related
    ENSCAFP00845021714.1, ENSCAFT00845027597.1
    Conserved Domains (2) summary
    pfam00233
    Location:188 → 404
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08499
    Location:47 → 103
    PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

  7. XM_038446696.1 → XP_038302624.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X5

    UniProtKB/TrEMBL
    A0A8P0P2F3
    Conserved Domains (2) summary
    pfam00233
    Location:184 → 400
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08499
    Location:43 → 99
    PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

  8. XM_038446693.1 → XP_038302621.1  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X2

    UniProtKB/TrEMBL
    A0A8C0MTH3
    Conserved Domains (2) summary
    pfam00233
    Location:218 → 434
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08499
    Location:77 → 133
    PDEase_I_N; 3'5'-cyclic nucleotide phosphodiesterase N-terminal

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049296.1 Alternate UMICH_Zoey_3.1

    Range
    25542676..25772033 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049777.1 Alternate UNSW_CanFamBas_1.0

    Range
    25472278..25701927 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049257.1 Alternate UU_Cfam_GSD_1.0

    Range
    25608455..25838496 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006618.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    25212919..25448739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
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