ABCC2 ATP binding cassette subfamily C member 2 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: ABCC2provided by VGNC
Official Full Name: ATP binding cassette subfamily C member 2provided by VGNC
Primary source: VGNC:VGNC:37440
See related: Ensembl:ENSCAFG00845030901
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: MRP2
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 28

Exon count:: 31

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	28	NC_051832.1 (13138667..13208016)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	28	NC_006610.4 (12854192..12923368)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	28	NC_049249.1 (12857984..12927300)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	28	NC_049288.1 (12685440..12754683)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	28	NC_049769.1 (12716120..12786599)

Chromosome 28 - NC_051832.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ABC-type transporter activity	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in apical plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ATP-binding cassette sub-family C member 2

Names: multidrug resistance associated protein 2; multidrug resistance protein 2

NP_001003081.1

EC 7.6.2.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003081.1 → NP_001003081.1 ATP-binding cassette sub-family C member 2

See identical proteins and their annotated locations for NP_001003081.1

Status: PROVISIONAL

Source sequence(s)

Y18220

UniProtKB/TrEMBL

A0A8C0NR86, A0A8I3QZD7, Q9GK09

Related

ENSCAFP00845043230.1, ENSCAFT00845054981.1

Conserved Domains (6) summary

TIGR00957
Location:8 → 1499

MRP_assoc_pro; multi drug resistance-associated protein (MRP)

cd03244
Location:1297 → 1502

ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein

cd03250
Location:637 → 838

ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C

pfam00664
Location:982 → 1248

ABC_membrane; ABC transporter transmembrane region

pfam16185
Location:26 → 181

MTABC_N; Mitochondrial ABC-transporter N-terminal five TM region

cl00549
Location:326 → 593

ABC_membrane; ABC transporter transmembrane region