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IL15 interleukin 15 [ Canis lupus familiaris (dog) ]

Gene ID: 403584, updated on 5-Mar-2024

Summary

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Official Symbol
IL15provided by VGNC
Official Full Name
interleukin 15provided by VGNC
Primary source
VGNC:VGNC:41939
See related
Ensembl:ENSCAFG00845019627
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 19 NC_051823.1 (1361003..1425159, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 19 NC_006601.4 (1586489..1611118, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 19 NC_049240.1 (2058426..2083219, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 19 NC_049279.1 (1341699..1366271, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 19 NC_049760.1 (1703298..1727862, complement)

Chromosome 19 - NC_051823.1Genomic Context describing neighboring genes Neighboring gene putative protein TPRXL Neighboring gene uncharacterized LOC111091039 Neighboring gene uncharacterized LOC111091040 Neighboring gene uncharacterized LOC111091041

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Uropathogenic E. coli promote a paracellular urothelial barrier defect characterized by altered tight junction integrity, epithelial cell sloughing and cytokine release. Wood MW, et al. J Comp Pathol, 2012 Jul. PMID 22014415, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This study points to a potential role for IL-15 in urinary tract infection-induced uro-thelial injury.
    Title: Uropathogenic E. coli promote a paracellular urothelial barrier defect characterized by altered tight junction integrity, epithelial cell sloughing and cytokine release.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neutrophil activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of T cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytokine production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of tyrosine phosphorylation of STAT protein IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001197188.1 → NP_001184117.1  interleukin-15

    Status: VALIDATED

    Source sequence(s)
    DN269137, DN879783, JAAUVH010000115
    UniProtKB/TrEMBL
    A0A8C0L9N7, A0A8C0L9P6, A0A8C0NA66, A0A8P0S9D1
    Related
    ENSCAFP00845027216.1, ENSCAFT00845034752.1
    Conserved Domains (1) summary
    pfam02372
    Location:33 → 154
    IL15; Interleukin 15

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051823.1 Reference ROS_Cfam_1.0

    Range
    1361003..1425159 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038425560.1 → XP_038281488.1  interleukin-15 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L9N7, A0A8I3S443
    Conserved Domains (1) summary
    pfam02372
    Location:33 → 154
    IL15; Interleukin 15

  2. XM_038425561.1 → XP_038281489.1  interleukin-15 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L9N7, A0A8I3S443
    Conserved Domains (1) summary
    pfam02372
    Location:33 → 154
    IL15; Interleukin 15

  3. XM_038425562.1 → XP_038281490.1  interleukin-15 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L9N7, A0A8I3S443
    Conserved Domains (1) summary
    pfam02372
    Location:33 → 154
    IL15; Interleukin 15

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049279.1 Alternate UMICH_Zoey_3.1

    Range
    1341699..1366271 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049760.1 Alternate UNSW_CanFamBas_1.0

    Range
    1703298..1727862 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049240.1 Alternate UU_Cfam_GSD_1.0

    Range
    2058426..2083219 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006601.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    1586489..1611118 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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