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PRKACA protein kinase cAMP-activated catalytic subunit alpha [ Canis lupus familiaris (dog) ]

Gene ID: 403556, updated on 5-Mar-2024

Summary

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Official Symbol
PRKACAprovided by VGNC
Official Full Name
protein kinase cAMP-activated catalytic subunit alphaprovided by VGNC
Primary source
VGNC:VGNC:59441
See related
Ensembl:ENSCAFG00845024723
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See PRKACA in Genome Data Viewer
Location:
chromosome: 20
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (48926811..48944065)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (48283546..48299768)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (48807387..48823603)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (48138017..48154228)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (48564570..48580793)

Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor L1 Neighboring gene uncharacterized LOC119864728 Neighboring gene anti-silencing function 1B histone chaperone Neighboring gene chromosome 20 C19orf67 homolog Neighboring gene sterile alpha motif domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts. Asai M, et al. J Mol Cell Cardiol, 2009 Apr. PMID 19059265

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PKA rapidly enhances proteasome assembly and activity in in vivo hearts.
    Title: PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cAMP-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase A regulatory subunit binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein kinase A signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of cAMP-dependent protein kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cAMP-dependent protein kinase catalytic subunit alpha
Names
PKA C-alpha
protein kinase A alpha
protein kinase, cAMP-dependent, catalytic, alpha
NP_001003032.1
XP_038282279.1
XP_038282280.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003032.1 → NP_001003032.1  cAMP-dependent protein kinase catalytic subunit alpha

    See identical proteins and their annotated locations for NP_001003032.1

    Status: PROVISIONAL

    Source sequence(s)
    AF525132
    UniProtKB/Swiss-Prot
    Q8MJ44
    UniProtKB/TrEMBL
    A0A8C0T563, A0A8I3Q5M5
    Related
    ENSCAFP00845034366.1, ENSCAFT00845043855.1
    Conserved Domains (2) summary
    smart00220
    Location:43 → 297
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14209
    Location:41 → 330
    STKc_PKA; Catalytic subunit of the Serine/Threonine Kinase, cAMP-dependent protein kinase

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051824.1 Reference ROS_Cfam_1.0

    Range
    48926811..48944065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038426352.1 → XP_038282280.1  cAMP-dependent protein kinase catalytic subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A8C0T4U7, A0A8C0T563, A0A8I3PTD4, A0A8I3Q5M5
    Related
    ENSCAFP00845034436.1, ENSCAFT00845043941.1
    Conserved Domains (1) summary
    cd14209
    Location:34 → 323
    STKc_PKA; Catalytic subunit of the Serine/Threonine Kinase, cAMP-dependent protein kinase

  2. XM_038426351.1 → XP_038282279.1  cAMP-dependent protein kinase catalytic subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C0T563, A0A8I3Q5M5
    Conserved Domains (1) summary
    cd14209
    Location:84 → 373
    STKc_PKA; Catalytic subunit of the Serine/Threonine Kinase, cAMP-dependent protein kinase

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049280.1 Alternate UMICH_Zoey_3.1

    Range
    48138017..48154228
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

    Range
    48564570..48580793
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

    Range
    48807387..48823603
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    48283546..48299768
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MJ44.3 GenPept UniProtKB/Swiss-Prot:Q8MJ44

Gene LinkOut

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