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CD40LG CD40 ligand [ Canis lupus familiaris (dog) ]

Gene ID: 403468, updated on 5-Mar-2024

Summary

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Official Symbol
CD40LGprovided by VGNC
Official Full Name
CD40 ligandprovided by VGNC
Primary source
VGNC:VGNC:38959
See related
Ensembl:ENSCAFG00845029290
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
CD154; TNFSF5; TNLG8B
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (108980873..109002662)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (92832126..92844241)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (107964432..107976548)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (106131221..106143392)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (108322638..108334748)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene succinate dehydrogenase assembly factor 1, mitochondrial-like Neighboring gene Rac/Cdc42 guanine nucleotide exchange factor 6 Neighboring gene uncharacterized LOC102154490 Neighboring gene small nucleolar RNA SNORD61 Neighboring gene RNA binding motif protein X-linked

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative genomic analysis of eutherian tumor necrosis factor ligand genes. Premzl M. Immunogenetics, 2016 Feb. PMID 26646413

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CD40 ligand
Names
CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome)
CD40-L
tumor necrosis factor (ligand) superfamily, member 5
tumor necrosis factor ligand 8B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002981.1 → NP_001002981.1  CD40 ligand

    See identical proteins and their annotated locations for NP_001002981.1

    Status: PROVISIONAL

    Source sequence(s)
    AY333790
    UniProtKB/Swiss-Prot
    O97626
    UniProtKB/TrEMBL
    A0A0U5J6Y6, A0A8C0LPD6
    Related
    ENSCAFP00845040687.1, ENSCAFT00845051855.1
    Conserved Domains (1) summary
    pfam00229
    Location:137 → 260
    TNF; TNF(tumor Necrosis Factor) family

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    108980873..109002662
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038448790.1 → XP_038304718.1  CD40 ligand isoform X2

    UniProtKB/TrEMBL
    A0A8C0LPD6
    Conserved Domains (1) summary
    pfam00229
    Location:102 → 225
    TNF; TNF(tumor Necrosis Factor) family

  2. XM_038448789.1 → XP_038304717.1  CD40 ligand isoform X2

    UniProtKB/TrEMBL
    A0A8C0LPD6
    Conserved Domains (1) summary
    pfam00229
    Location:102 → 225
    TNF; TNF(tumor Necrosis Factor) family

  3. XM_038448788.1 → XP_038304716.1  CD40 ligand isoform X1

    UniProtKB/TrEMBL
    A0A8C0LPD6
    Conserved Domains (1) summary
    pfam00229
    Location:105 → 228
    TNF; TNF(tumor Necrosis Factor) family

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    106131221..106143392
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    108322638..108334748
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    107964432..107976548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    92832126..92844241
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O97626.1 GenPept UniProtKB/Swiss-Prot:O97626

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