U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

IL2RB interleukin 2 receptor subunit beta [ Canis lupus familiaris (dog) ]

Gene ID: 403439, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
IL2RBprovided by VGNC
Official Full Name
interleukin 2 receptor subunit betaprovided by VGNC
Primary source
VGNC:VGNC:41978
See related
Ensembl:ENSCAFG00845007511
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 10
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (28162844..28180818)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (27325543..27343512)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (28371136..28389104)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (27884492..27902458)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (28193229..28211199)

Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene somatostatin receptor 3 Neighboring gene C1q and TNF related 6 Neighboring gene uncharacterized LOC119873634 Neighboring gene transmembrane serine protease 6 Neighboring gene uncharacterized LOC119873635 Neighboring gene potassium channel tetramerization domain containing 17

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. All subunits of the interleukin-2 receptor are expressed by canine cutaneous mast cell tumours. Meyer A, et al. J Comp Pathol, 2013 Jul. PMID 23276382

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immunoglobulin mediated immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
interleukin-2 receptor subunit beta
Names
IL 2/15 receptor beta chain
interleukin 2 receptor, beta

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001286850.1 → NP_001273779.1  interleukin-2 receptor subunit beta isoform 2 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1.
    Source sequence(s)
    JAAUVH010000358
    UniProtKB/TrEMBL
    A0A8C0JUI9
    Conserved Domains (1) summary
    smart00060
    Location:135 → 217
    FN3; Fibronectin type 3 domain

  2. NM_001286851.1 → NP_001273780.1  interleukin-2 receptor subunit beta isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    JAAUVH010000358
    UniProtKB/TrEMBL
    A0A8C0JUI9, A0A8C0MT13, A0A8I3MVN6
    Related
    ENSCAFP00845010307.1, ENSCAFT00845013269.1
    Conserved Domains (1) summary
    smart00060
    Location:136 → 218
    FN3; Fibronectin type 3 domain

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051814.1 Reference ROS_Cfam_1.0

    Range
    28162844..28180818
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038678742.1 → XP_038534670.1  interleukin-2 receptor subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0MUJ3
    Conserved Domains (2) summary
    smart00060
    Location:120 → 202
    FN3; Fibronectin type 3 domain
    pfam18707
    Location:18 → 109
    IL2RB_N1; Interleukin-2 receptor subunit beta N-terminal domain 1

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049270.1 Alternate UMICH_Zoey_3.1

    Range
    27884492..27902458
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

    Range
    28193229..28211199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

    Range
    28371136..28389104
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    27325543..27343512
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001197068.1: Suppressed sequence

    Description
    NM_001197068.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.