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Polr3E RNA polymerase III subunit E [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40325, updated on 4-Apr-2024

Summary

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Official Symbol
Polr3Eprovided by FlyBase
Official Full Name
RNA polymerase III subunit Eprovided by FlyBase
Primary source
FLYBASE:FBgn0028402
Locus tag
Dmel_CG10582
See related
AllianceGenome:FB:FBgn0028402
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10582; Dmel\CG10582; RPC37; sin; Sin
Summary
Predicted to be involved in transcription, DNA-templated. Predicted to be part of RNA polymerase III complex. Is expressed in organism. Orthologous to human POLR3E (RNA polymerase III subunit E). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Polr3E in Genome Data Viewer
Location:
78A5-78A5; 3-47 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21031825..21033561)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21024925..21026661)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45801 Neighboring gene uncharacterized protein Neighboring gene Decaprenyl diphosphate synthase subunit 2 Neighboring gene uncharacterized protein Neighboring gene schizo Neighboring gene uncharacterized protein Neighboring gene knockout Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SIN, a novel Drosophila protein that associates with the RNA binding protein sex-lethal. Dong Z, et al. Gene, 1999 Sep 17. PMID 10521666
  2. Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis. Pizzo L, et al. PLoS Genet, 2021 Apr. PMID 33819264, Free PMC Article
  3. In silico identification of Drosophila melanogaster genes encoding RNA polymerase subunits. Marygold SJ, et al. MicroPubl Biol, 2020 Oct 20. PMID 33274328, Free PMC Article
  4. Advances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway. Fisher KH, et al. BMC Genomics, 2012 Sep 24. PMID 23006893, Free PMC Article
  5. Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development. Yusuff T, et al. PLoS Genet, 2020 Jun. PMID 32579612, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA transcription by RNA polymerase III IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RNA polymerase III subunit E
Names
CG10582-PA
CG10582-PC
Polr3E-PA
Polr3E-PC
Sex-lethal interactor

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    21031825..21033561
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001170015.2 → NP_001163486.2  RNA polymerase III subunit E, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163486.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JI58, Q9U778
    Conserved Domains (1) summary
    pfam04801
    Location:9 → 443
    Sin_N; Sin-like protein conserved region

  2. NM_079468.4 → NP_524192.2  RNA polymerase III subunit E, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524192.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U778, Q9VP85
    Related
    FBpp0077946
    Conserved Domains (1) summary
    pfam04801
    Location:4 → 444
    Sin_N; Sin-like protein conserved region
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E1JI58 E1JI58
Q5BI58 Q5BI58
Q9U778 Q9U778
Q9VP85 Q9VP85

Gene LinkOut

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