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frmpd4 FERM and PDZ domain containing 4 [ Danio rerio (zebrafish) ]

Gene ID: 403129, updated on 27-Mar-2024

Summary

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Official Symbol
frmpd4provided by ZNC
Official Full Name
FERM and PDZ domain containing 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-121004-1
See related
Ensembl:ENSDARG00000075685 AllianceGenome:ZFIN:ZDB-GENE-121004-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 104. Orthologous to human FRMPD4 (FERM and PDZ domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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See frmpd4 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (54039437..54129172)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (54505972..54561747)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene component of oligomeric golgi complex 3 Neighboring gene midline 1 Neighboring gene toll-like receptor 7 Neighboring gene toll-like receptor 8 Neighboring gene toll-like receptor 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Zebrafish peptidoglycan recognition protein SC (zfPGRP-SC) mediates multiple intracellular signaling pathways. Chang MX, et al. Fish Shellfish Immunol, 2009 Feb. PMID 19084604
  2. Evolution of the zebrafish model: from development to immunity and infectious disease. Phelps HA, et al. Zebrafish, 2005. PMID 18248169
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
FERM and PDZ domain-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    54039437..54129172
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021479059.1 → XP_021334734.1  FERM and PDZ domain-containing protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8M9QBQ2
    Related
    ENSDARP00000102225.4, ENSDART00000112441.4
    Conserved Domains (3) summary
    smart00295
    Location:206 → 425
    B41; Band 4.1 homologues
    cd00992
    Location:77 → 153
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13183
    Location:421 → 525
    FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)

  2. XM_021479058.1 → XP_021334733.1  FERM and PDZ domain-containing protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q5Q1
    Conserved Domains (3) summary
    smart00295
    Location:206 → 425
    B41; Band 4.1 homologues
    cd00992
    Location:77 → 153
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13183
    Location:421 → 525
    FERM_C_FRMPD1_FRMPD3_FRMPD4; FERM domain C-lobe of FERM and PDZ domain containing proteins 1, 3, and 4 (FRMPD1, 3, 4)
Nucleotide Protein Strain
Heading Accession and Version

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