prpf3 PRP3 pre-mRNA processing factor 3 homolog (yeast) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: prpf3provided by ZNC
Official Full Name: PRP3 pre-mRNA processing factor 3 homolog (yeast)provided by ZNC
Primary source: ZFIN:ZDB-GENE-040823-3
See related: Ensembl:ENSDARG00000086425 AllianceGenome:ZFIN:ZDB-GENE-040823-3
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: HPRP3; HPRP3P; wu:fa11f05
Summary: Acts upstream of or within retina development in camera-type eye. Predicted to be located in nucleus. Predicted to be part of U4/U6 x U5 tri-snRNP complex. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 18. Orthologous to human PRPF3 (pre-mRNA processing factor 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (9432622..9453573, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (9541720..9562671, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fa11f05.s1 (e-PCR)
- UniSTS:202316

AA494840 (e-PCR)
- UniSTS:205395

fe37e05.x1 (e-PCR)
- UniSTS:196436

fe06c12.x1 (e-PCR)
- UniSTS:196022

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within retina development in camera-type eye	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of U4/U6 x U5 tri-snRNP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of U4/U6 x U5 tri-snRNP complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: U4/U6 small nuclear ribonucleoprotein Prp3

Names: U4/U6-associated RNA splicing factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205748.2 → NP_991311.2 U4/U6 small nuclear ribonucleoprotein Prp3

See identical proteins and their annotated locations for NP_991311.2

Status: PROVISIONAL

Source sequence(s)

BC139603

UniProtKB/TrEMBL

A4QP06

Related

ENSDARP00000107223.2, ENSDART00000126154.4

Conserved Domains (3) summary

pfam01480
Location:9 → 76

PWI; PWI domain

pfam06544
Location:565 → 688

DUF1115; Protein of unknown function (DUF1115)

pfam08572
Location:328 → 540

PRP3; pre-mRNA processing factor 3 (PRP3)