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sh3glb2a SH3-domain GRB2-like endophilin B2a [ Danio rerio (zebrafish) ]

Gene ID: 402885, updated on 3-Apr-2024

Summary

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Official Symbol
sh3glb2aprovided by ZNC
Official Full Name
SH3-domain GRB2-like endophilin B2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-061201-8
See related
Ensembl:ENSDARG00000008983 AllianceGenome:ZFIN:ZDB-GENE-061201-8
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:111880; zgc:158183
Summary
Predicted to be involved in membrane organization. Predicted to be located in cytoplasm. Predicted to be active in membrane. Orthologous to human SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See sh3glb2a in Genome Data Viewer
Location:
chromosome: 8
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (2757419..2789645)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (2698893..2731842)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene estrogen-induced osteoclastogenesis regulator 1a Neighboring gene uncharacterized LOC110440004 Neighboring gene proline-rich transmembrane protein 1 Neighboring gene crumbs cell polarity complex component 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution and Expression of Paxillin Genes in Teleost Fish. Jacob AE, et al. PLoS One, 2016. PMID 27806088, Free PMC Article
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC111880

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in membrane organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
endophilin-B2; endophilin-B2a
Names
SH3-domain GRB2-like endophilin B2
sh3glb2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039998.2 → NP_001035087.2  endophilin-B2a

    Status: VALIDATED

    Source sequence(s)
    CABZ01085196, CABZ01085197, CABZ01088719, FP325112
    Related
    ENSDARP00000051402.7, ENSDART00000051403.8

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    2757419..2789645
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017357307.2 → XP_017212796.1  endophilin-B2 isoform X6

    UniProtKB/TrEMBL
    A0A0R4IG19, A0A8M6Z0F4, Q502S2
    Related
    ENSDARP00000132194.1, ENSDART00000160551.2

  2. XM_017357302.2 → XP_017212791.1  endophilin-B2 isoform X1

    UniProtKB/TrEMBL
    A0A8M6Z0F0, Q502S2

  3. XM_017357303.2 → XP_017212792.1  endophilin-B2 isoform X2

    UniProtKB/TrEMBL
    A0A8M6Z221, Q502S2

  4. XM_017357305.2 → XP_017212794.1  endophilin-B2 isoform X4

    UniProtKB/TrEMBL
    A0A8M6YZR1, Q502S2

  5. XM_017357306.2 → XP_017212795.1  endophilin-B2 isoform X5

    UniProtKB/TrEMBL
    A0A8M6Z7K7, Q502S2

  6. XM_017357304.2 → XP_017212793.1  endophilin-B2 isoform X3

    UniProtKB/TrEMBL
    A0A8M6Z818, Q502S2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_205593.1: Suppressed sequence

    Description
    NM_205593.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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