eno2 enolase 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: eno2provided by ZNC
Official Full Name: enolase 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-040704-27
See related: Ensembl:ENSDARG00000014287 AllianceGenome:ZFIN:ZDB-GENE-040704-27
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: eno3; fc09h05; zgc:92418; wu:fc09h05
Summary: Predicted to enable phosphopyruvate hydratase activity. Predicted to be involved in glycolytic process. Predicted to be part of phosphopyruvate hydratase complex. Is expressed in musculature system; nervous system; neural tube; presumptive neural retina; and trigeminal placode. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human ENO2 (enolase 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 19

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (5072913..5091687)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (5156400..5175201)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Endogenous eno2 mRNA was detected in the developing retina from 2 days post-fertilization (dpf), and by 12dpf was localized to the retinal ganglion cell, inner and outer nuclear layers.
Title: Expression of a 12-kb promoter element derived from the zebrafish enolase-2 gene in the zebrafish visual system.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info
enables phosphopyruvate hydratase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphopyruvate hydratase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glycolytic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within glycolytic process	IEA Inferred from Electronic Annotation more info
involved_in glycolytic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of phosphopyruvate hydratase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of phosphopyruvate hydratase complex	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: gamma-enolase

NP_001003848.1

EC 4.2.1.11

XP_009292264.1

EC 4.2.1.11

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001003848.2 → NP_001003848.1 gamma-enolase

See identical proteins and their annotated locations for NP_001003848.1

Status: PROVISIONAL

Source sequence(s)

BC072713

UniProtKB/TrEMBL

A0A2R8QDG2, F6P177, Q6GQM9

Related

ENSDARP00000032456.5, ENSDART00000037126.7

Conserved Domains (2) summary

PLN00191
Location:2 → 432

PLN00191; enolase

cd03313
Location:5 → 416

enolase; Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007130.7 Reference GRCz11 Primary Assembly

Range

5072913..5091687

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009293989.3 → XP_009292264.1 gamma-enolase isoform X1

UniProtKB/TrEMBL

A0A8M3B3A2

Conserved Domains (2) summary

PLN00191
Location:2 → 340

PLN00191; enolase

cd03313
Location:1 → 324

enolase; Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.