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MYL1 myosin, light chain 1, alkali; skeletal, fast [ Gallus gallus (chicken) ]

Gene ID: 396470, updated on 11-Apr-2024

Summary

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Official Symbol
MYL1provided by CGNC
Official Full Name
myosin, light chain 1, alkali; skeletal, fastprovided by CGNC
Primary source
CGNC:49821
See related
Ensembl:ENSGALG00010011505
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
MLC; MLC-1; MLC-3
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
9
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (2847286..2865335, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (2787036..2805085, complement)

Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene KAT8 regulatory NSL complex subunit 1 like Neighboring gene acyl-CoA dehydrogenase, long chain Neighboring gene carbamoyl-phosphate synthase 1 Neighboring gene LanC like 1 Neighboring gene uncharacterized LOC121111314

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Orientation of the N-terminal lobe of the myosin regulatory light chain in skeletal muscle fibers. Romano D, et al. Biophys J, 2012 Mar 21. PMID 22455925, Free PMC Article
  2. The primary structure of L-1 light chain of chicken fast skeletal muscle myosin and its genetic implication. Matsuda G, et al. FEBS Lett, 1981 Apr 6. PMID 7238855
  3. Amino-acid sequence of the L-1 light chain of chicken fast skeletal-muscle myosin. Umegane T, et al. Hoppe Seylers Z Physiol Chem, 1982 Nov. PMID 7173826
  4. Amino-acid sequence of the L-4 light chain of chicken skeletal-muscle myosin. Maita T, et al. Eur J Biochem, 1981. PMID 6783403
  5. Alternative transcription and two modes of splicing results in two myosin light chains from one gene. Nabeshima Y, et al. Nature, 1984 Mar 22-28. PMID 6709041

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Metastasis of aggressive amoeboid sarcoma cells is dependent on Rho/ROCK/MLC signaling.
    Title: Metastasis of aggressive amoeboid sarcoma cells is dependent on Rho/ROCK/MLC signaling.
  2. Fiber fluorescence data were interpreted using the crystal structure of the head domain of chicken skeletal myosin in the nucleotide-free state.
    Title: Orientation of the N-terminal lobe of the myosin regulatory light chain in skeletal muscle fibers.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in contractile muscle fiber IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of myosin II complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myosin light chain 1, skeletal muscle isoform
Names
alkali myosin light chain 1
alkali myosin light chain 3
light polypeptide 1
myosin a1
myosin light chain 1f
myosin light chain 3f
myosin light chain A1
myosin light chain A2
myosin light chain alkali 1
myosin light chain alkali 2
myosin, light polypeptide 1, alkali; skeletal, fast
skeletal-muscle myosin L-1 light chain
skeletal-muscle myosin L-4 light chain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044632.2 → NP_001038097.2  myosin light chain 1, skeletal muscle isoform

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000235
    UniProtKB/Swiss-Prot
    P02605, Q90896
    UniProtKB/TrEMBL
    A0A8V0Y563
    Related
    ENSGALP00010015776.1, ENSGALT00010027547.1
    Conserved Domains (1) summary
    PTZ00184
    Location:4 → 149
    PTZ00184; calmodulin; Provisional

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2847286..2865335 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015289140.4 → XP_015144626.2  myosin light chain 1, skeletal muscle isoform isoform X1

    UniProtKB/Swiss-Prot
    P02604, Q90895, Q9PWQ5
    UniProtKB/TrEMBL
    A0A8V0YDM6
    Related
    ENSGALP00010015779.1, ENSGALT00010027551.1
    Conserved Domains (1) summary
    PTZ00184
    Location:43 → 191
    PTZ00184; calmodulin; Provisional

  2. XM_015289141.4 → XP_015144627.2  myosin light chain 1, skeletal muscle isoform isoform X1

    UniProtKB/Swiss-Prot
    P02604, Q90895, Q9PWQ5
    UniProtKB/TrEMBL
    A0A8V0YDM6
    Conserved Domains (1) summary
    PTZ00184
    Location:43 → 191
    PTZ00184; calmodulin; Provisional

  3. XM_040703372.2 → XP_040559306.1  myosin light chain 1, skeletal muscle isoform isoform X3

    UniProtKB/Swiss-Prot
    P02605, Q90896
    UniProtKB/TrEMBL
    A0A8V0Y563
    Conserved Domains (1) summary
    PTZ00184
    Location:4 → 149
    PTZ00184; calmodulin; Provisional

  4. XM_040703371.2 → XP_040559305.1  myosin light chain 1, skeletal muscle isoform isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y563
    Conserved Domains (1) summary
    PTZ00184
    Location:2 → 150
    PTZ00184; calmodulin; Provisional

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2787036..2805085 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046921214.1 → XP_046777170.1  myosin light chain 1, skeletal muscle isoform isoform X1

    UniProtKB/TrEMBL
    A0A8V0YDM6

  2. XM_046921215.1 → XP_046777171.1  myosin light chain 1, skeletal muscle isoform isoform X1

    UniProtKB/TrEMBL
    A0A8V0YDM6

  3. XM_046921217.1 → XP_046777173.1  myosin light chain 1, skeletal muscle isoform isoform X3

    UniProtKB/Swiss-Prot
    P02605, Q90896

  4. XM_046921216.1 → XP_046777172.1  myosin light chain 1, skeletal muscle isoform isoform X2

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P02604.3 GenPept UniProtKB/Swiss-Prot:P02604
P02605.3 GenPept UniProtKB/Swiss-Prot:P02605

Gene LinkOut

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