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CHRM3 cholinergic receptor muscarinic 3 [ Gallus gallus (chicken) ]

Gene ID: 396364, updated on 3-Apr-2024

Summary

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Symbol
CHRM3provided by CGNC
Full Name
cholinergic receptor muscarinic 3provided by CGNC
Primary source
CGNC:49770
See related
Ensembl:ENSGALG00010008996
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CHRM1; MACHR
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (36071629..36330735, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (35976407..36235502, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene formin 2 Neighboring gene uncharacterized LOC121110227 Neighboring gene uncharacterized LOC101751758 Neighboring gene uncharacterized LOC775999

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A high-resolution linkage map of human 9q34.1. Henske EP, et al. Genomics, 1993 Sep. PMID 8244374
  2. A novel M3 muscarinic acetylcholine receptor is expressed in chick atrium and ventricle. Gadbut AP, et al. J Biol Chem, 1994 Oct 14. PMID 7929287
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled acetylcholine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G protein-coupled serotonin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of smooth muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of vascular associated smooth muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in saliva secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
muscarinic acetylcholine receptor M3
Names
M3 muscarinic acetylcholine receptor
cholinergic receptor muscarinic 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396514.1 → NP_001383443.1  muscarinic acetylcholine receptor M3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000063
    UniProtKB/Swiss-Prot
    P49578
    Conserved Domains (3) summary
    cd15299
    Location:89 → 293
    7tmA_mAChR_M3; muscarinic acetylcholine receptor subtype M3, member of the class A family of seven-transmembrane G protein-coupled receptors
    cd14964
    Location:515 → 537
    7tm_GPCRs; TM helix 6 [structural motif]
    cl28897
    Location:509 → 588
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. NM_205399.2 → NP_990730.2  muscarinic acetylcholine receptor M3 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000063
    UniProtKB/Swiss-Prot
    P49578
    Conserved Domains (3) summary
    cd15299
    Location:114 → 318
    7tmA_mAChR_M3; muscarinic acetylcholine receptor subtype M3, member of the class A family of seven-transmembrane G protein-coupled receptors
    cd14964
    Location:540 → 562
    7tm_GPCRs; TM helix 6 [structural motif]
    cl28897
    Location:534 → 613
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    36071629..36330735 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046938562.1 → XP_046794518.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5
    Related
    ENSGALP00010012223.1, ENSGALT00010021453.1

  2. XM_046938561.1 → XP_046794517.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5

  3. XM_046938564.1 → XP_046794520.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5
    Related
    ENSGALP00010012204.1, ENSGALT00010021423.1

  4. XM_046938563.1 → XP_046794519.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5
    Related
    ENSGALP00010012220.1, ENSGALT00010021447.1

  5. XM_046938559.1 → XP_046794515.1  muscarinic acetylcholine receptor M3 isoform X1

  6. XM_046938560.1 → XP_046794516.1  muscarinic acetylcholine receptor M3 isoform X1

  7. XM_046938566.1 → XP_046794522.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5
    Related
    ENSGALP00010012203.1, ENSGALT00010021417.1

  8. XM_046938565.1 → XP_046794521.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5

  9. XM_046938569.1 → XP_046794525.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5
    Related
    ENSGALP00010012198.1, ENSGALT00010021406.1

  10. XM_046938567.1 → XP_046794523.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5
    Related
    ENSGALP00010012195.1, ENSGALT00010021402.1

  11. XM_046938568.1 → XP_046794524.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    35976407..36235502 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046913297.1 → XP_046769253.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5

  2. XM_046913296.1 → XP_046769252.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5

  3. XM_046913299.1 → XP_046769255.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5

  4. XM_046913298.1 → XP_046769254.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5

  5. XM_046913294.1 → XP_046769250.1  muscarinic acetylcholine receptor M3 isoform X1

  6. XM_046913295.1 → XP_046769251.1  muscarinic acetylcholine receptor M3 isoform X1

  7. XM_046913301.1 → XP_046769257.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5

  8. XM_046913300.1 → XP_046769256.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5

  9. XM_046913304.1 → XP_046769260.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5

  10. XM_046913302.1 → XP_046769258.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5

  11. XM_046913303.1 → XP_046769259.1  muscarinic acetylcholine receptor M3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XVB5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P49578.1 GenPept UniProtKB/Swiss-Prot:P49578

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