MYLK2 myosin light chain kinase 2 [Gallus gallus (chicken)] - Gene

Summary

Symbol: MYLK2provided by CGNC
Full Name: myosin light chain kinase 2provided by CGNC
Primary source: CGNC:4713
See related: Ensembl:ENSGALG00010013029
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	20	NC_052551.1 (10394057..10400969)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	20	NC_052592.1 (10175711..10182623)

Chromosome 20 - NC_052551.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables myosin light chain kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: myosin light chain kinase 2, skeletal/cardiac muscle

Names: Gallus domesticus skeletal muscle; myosin light chain kinase 2, skeletal muscle

NP_990723.2

EC 2.7.11.18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205392.2 → NP_990723.2 myosin light chain kinase 2, skeletal/cardiac muscle

Status: VALIDATED

Source sequence(s)

JAENSK010000328

UniProtKB/TrEMBL

A0A8V0YPY7, A2NBE2

Related

ENSGALP00010018210.1, ENSGALT00010031245.1

Conserved Domains (2) summary

PHA03247
Location:21 → 470

PHA03247; large tegument protein UL36; Provisional

cd14190
Location:508 → 768

STKc_MLCK2; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 2