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TCF12 transcription factor 12 [ Gallus gallus (chicken) ]

Gene ID: 396334, updated on 3-Apr-2024

Summary

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Symbol
TCF12provided by CGNC
Full Name
transcription factor 12provided by CGNC
Primary source
CGNC:49756
See related
Ensembl:ENSGALG00010023170
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
28
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (7424009..7610828, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (7296981..7483774, complement)

Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107052129 Neighboring gene aldehyde dehydrogenase 1 family member A2 Neighboring gene myocardial zonula adherens protein Neighboring gene cingulin like 1 Neighboring gene zinc finger protein 280D Neighboring gene testis expressed 9 Neighboring gene meiosis specific nuclear structural 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CTF4, a chicken transcription factor of the helix-loop-helix class A family. Tsay HJ, et al. Nucleic Acids Res, 1992 Apr 11. PMID 1579475, Free PMC Article
  2. Cloning and analysis of a new developmentally regulated member of the basic helix-loop-helix family. Helms JA, et al. Mech Dev, 1994 Nov. PMID 7873406
  3. ME1 and GE1: basic helix-loop-helix transcription factors expressed at high levels in the developing nervous system and in morphogenetically active regions. Neuman T, et al. Eur J Neurosci, 1993 Apr 1. PMID 8261111
  4. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor 12
Names
E-box-binding protein
TCF-12
basic helix-loop-helix protein
class A helix-loop-helix transcription factor GE1
transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)
transcription factor HTF-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205375.4 → NP_990706.2  transcription factor 12

    Status: PROVISIONAL

    Source sequence(s)
    BX935683, JAENSK010000245, U12974
    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    Conserved Domains (1) summary
    smart00353
    Location:508 → 561
    HLH; helix loop helix domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    7424009..7610828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040706208.2 → XP_040562142.1  transcription factor 12 isoform X1

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    UniProtKB/TrEMBL
    A0A8V0ZTR8
    Conserved Domains (1) summary
    cd18945
    Location:621 → 705
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  2. XM_040706218.2 → XP_040562152.1  transcription factor 12 isoform X6

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    UniProtKB/TrEMBL
    A0A8V0ZRR8
    Related
    ENSGALP00010034221.1, ENSGALT00010056478.1
    Conserved Domains (1) summary
    cd18945
    Location:596 → 680
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  3. XM_040706220.2 → XP_040562154.1  transcription factor 12 isoform X7

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    Conserved Domains (1) summary
    cd18945
    Location:596 → 680
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  4. XM_040706214.2 → XP_040562148.1  transcription factor 12 isoform X4

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    Conserved Domains (1) summary
    cd18945
    Location:597 → 681
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  5. XM_040706206.2 → XP_040562140.1  transcription factor 12 isoform X1

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    UniProtKB/TrEMBL
    A0A8V0ZTR8
    Related
    ENSGALP00010034223.1, ENSGALT00010056480.1
    Conserved Domains (1) summary
    cd18945
    Location:621 → 705
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  6. XM_040706216.2 → XP_040562150.1  transcription factor 12 isoform X6

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    UniProtKB/TrEMBL
    A0A8V0ZRR8
    Conserved Domains (1) summary
    cd18945
    Location:596 → 680
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  7. XM_040706219.2 → XP_040562153.1  transcription factor 12 isoform X7

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    Conserved Domains (1) summary
    cd18945
    Location:596 → 680
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  8. XM_040706213.2 → XP_040562147.1  transcription factor 12 isoform X4

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    Conserved Domains (1) summary
    cd18945
    Location:597 → 681
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  9. XM_040706210.2 → XP_040562144.1  transcription factor 12 isoform X2

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    Conserved Domains (1) summary
    cd18945
    Location:620 → 704
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  10. XM_040706211.2 → XP_040562145.1  transcription factor 12 isoform X3

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    UniProtKB/TrEMBL
    A0A8V0ZRS1
    Related
    ENSGALP00010034226.1, ENSGALT00010056483.1
    Conserved Domains (1) summary
    cd18945
    Location:620 → 704
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  11. XM_025153805.3 → XP_025009573.1  transcription factor 12 isoform X1

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    UniProtKB/TrEMBL
    A0A8V0ZTR8
    Conserved Domains (1) summary
    cd18945
    Location:621 → 705
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  12. XM_040706221.2 → XP_040562155.1  transcription factor 12 isoform X8

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    Conserved Domains (1) summary
    cd18945
    Location:595 → 679
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  13. XM_015278769.4 → XP_015134255.2  transcription factor 12 isoform X6

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    UniProtKB/TrEMBL
    A0A8V0ZRR8
    Conserved Domains (1) summary
    cd18945
    Location:596 → 680
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  14. XM_015278770.4 → XP_015134256.2  transcription factor 12 isoform X7

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    Conserved Domains (1) summary
    cd18945
    Location:596 → 680
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  15. XM_015278768.4 → XP_015134254.2  transcription factor 12 isoform X4

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    Conserved Domains (1) summary
    cd18945
    Location:597 → 681
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  16. XM_046898939.1 → XP_046754895.1  transcription factor 12 isoform X4

  17. XM_015278766.4 → XP_015134252.2  transcription factor 12 isoform X2

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    Conserved Domains (1) summary
    cd18945
    Location:620 → 704
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  18. XM_015278764.4 → XP_015134250.2  transcription factor 12 isoform X1

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    UniProtKB/TrEMBL
    A0A8V0ZTR8
    Conserved Domains (1) summary
    cd18945
    Location:621 → 705
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  19. XM_046898938.1 → XP_046754894.1  transcription factor 12 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZTR8

  20. XM_046898940.1 → XP_046754896.1  transcription factor 12 isoform X5

  21. XM_040706222.2 → XP_040562156.1  transcription factor 12 isoform X9

    UniProtKB/Swiss-Prot
    P30985, Q90622, Q9PSH1
    Conserved Domains (1) summary
    cd18945
    Location:571 → 655
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  22. XM_040706229.2 → XP_040562163.1  transcription factor 12 isoform X17

    Conserved Domains (1) summary
    cd18945
    Location:388 → 472
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  23. XM_040706225.2 → XP_040562159.1  transcription factor 12 isoform X12

    Conserved Domains (1) summary
    cd18945
    Location:412 → 496
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  24. XM_040706228.2 → XP_040562162.1  transcription factor 12 isoform X16

    Conserved Domains (1) summary
    cd18945
    Location:403 → 487
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  25. XM_046898941.1 → XP_046754897.1  transcription factor 12 isoform X14

  26. XM_040706223.2 → XP_040562157.1  transcription factor 12 isoform X11

    UniProtKB/TrEMBL
    A0A8V0ZRR3
    Related
    ENSGALP00010034216.1, ENSGALT00010056473.1
    Conserved Domains (1) summary
    cd18945
    Location:428 → 512
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  27. XM_015278773.4 → XP_015134259.1  transcription factor 12 isoform X15

    Conserved Domains (1) summary
    smart00353
    Location:415 → 468
    HLH; helix loop helix domain

  28. XM_015278772.4 → XP_015134258.1  transcription factor 12 isoform X13

    Conserved Domains (1) summary
    cd18945
    Location:404 → 488
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  29. XM_040706227.2 → XP_040562161.1  transcription factor 12 isoform X13

    Conserved Domains (1) summary
    cd18945
    Location:404 → 488
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  30. XM_015278771.3 → XP_015134257.1  transcription factor 12 isoform X10

    UniProtKB/TrEMBL
    A0A8V0ZTR0
    Related
    ENSGALP00010034213.1, ENSGALT00010056470.1
    Conserved Domains (1) summary
    cd18945
    Location:428 → 512
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  31. XM_040706224.2 → XP_040562158.1  transcription factor 12 isoform X10

    UniProtKB/TrEMBL
    A0A8V0ZTR0
    Conserved Domains (1) summary
    cd18945
    Location:428 → 512
    bHLH_E-protein_TCF4_E2-2; basic helix-loop-helix (bHLH) domain found in transcription factor 4 (TCF-4) and similar proteins

  32. XM_040706232.2 → XP_040562166.2  transcription factor 12 isoform X20

  33. XM_040706231.2 → XP_040562165.2  transcription factor 12 isoform X19

  34. XM_040706230.2 → XP_040562164.2  transcription factor 12 isoform X18

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    7296981..7483774 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046924558.1 → XP_046780514.1  transcription factor 12 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZTR8

  2. XM_046924569.1 → XP_046780525.1  transcription factor 12 isoform X6

    UniProtKB/TrEMBL
    A0A8V0ZRR8

  3. XM_046924572.1 → XP_046780528.1  transcription factor 12 isoform X7

  4. XM_046924564.1 → XP_046780520.1  transcription factor 12 isoform X4

  5. XM_046924556.1 → XP_046780512.1  transcription factor 12 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZTR8

  6. XM_046924568.1 → XP_046780524.1  transcription factor 12 isoform X6

    UniProtKB/TrEMBL
    A0A8V0ZRR8

  7. XM_046924571.1 → XP_046780527.1  transcription factor 12 isoform X7

  8. XM_046924563.1 → XP_046780519.1  transcription factor 12 isoform X4

  9. XM_046924559.1 → XP_046780515.1  transcription factor 12 isoform X2

  10. XM_046924561.1 → XP_046780517.1  transcription factor 12 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZRS1

  11. XM_046924555.1 → XP_046780511.1  transcription factor 12 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZTR8

  12. XM_046924573.1 → XP_046780529.1  transcription factor 12 isoform X8

  13. XM_046924567.1 → XP_046780523.1  transcription factor 12 isoform X6

    UniProtKB/TrEMBL
    A0A8V0ZRR8

  14. XM_046924570.1 → XP_046780526.1  transcription factor 12 isoform X7

  15. XM_046924562.1 → XP_046780518.1  transcription factor 12 isoform X4

  16. XM_046924565.1 → XP_046780521.1  transcription factor 12 isoform X4

  17. XM_046924560.1 → XP_046780516.1  transcription factor 12 isoform X2

  18. XM_046924554.1 → XP_046780510.1  transcription factor 12 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZTR8

  19. XM_046924557.1 → XP_046780513.1  transcription factor 12 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZTR8

  20. XM_046924566.1 → XP_046780522.1  transcription factor 12 isoform X5

  21. XM_046924574.1 → XP_046780530.1  transcription factor 12 isoform X9

  22. XM_046924584.1 → XP_046780540.1  transcription factor 12 isoform X17

  23. XM_046924578.1 → XP_046780534.1  transcription factor 12 isoform X12

  24. XM_046924583.1 → XP_046780539.1  transcription factor 12 isoform X16

  25. XM_046924580.1 → XP_046780536.1  transcription factor 12 isoform X14

  26. XM_046924576.1 → XP_046780532.1  transcription factor 12 isoform X11

    UniProtKB/TrEMBL
    A0A8V0ZRR3

  27. XM_046924582.1 → XP_046780538.1  transcription factor 12 isoform X15

  28. XM_046924579.1 → XP_046780535.1  transcription factor 12 isoform X13

  29. XM_046924581.1 → XP_046780537.1  transcription factor 12 isoform X13

  30. XM_046924575.1 → XP_046780531.1  transcription factor 12 isoform X10

    UniProtKB/TrEMBL
    A0A8V0ZTR0

  31. XM_046924577.1 → XP_046780533.1  transcription factor 12 isoform X10

    UniProtKB/TrEMBL
    A0A8V0ZTR0

  32. XM_046924588.1 → XP_046780544.1  transcription factor 12 isoform X20

  33. XM_046924587.1 → XP_046780543.1  transcription factor 12 isoform X19

  34. XM_046924585.1 → XP_046780541.1  transcription factor 12 isoform X18

  35. XM_046924586.1 → XP_046780542.1  transcription factor 12 isoform X21

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P30985.2 GenPept UniProtKB/Swiss-Prot:P30985

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