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CAPN11 calpain 11 [ Gallus gallus (chicken) ]

Gene ID: 396240, updated on 3-Apr-2024

Summary

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Official Symbol
CAPN11provided by CGNC
Official Full Name
calpain 11provided by CGNC
Primary source
CGNC:54348
See related
Ensembl:ENSGALG00010019641
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CANP; mu/mCAPN; mu/m-CAPN
Orthologs
human mouse all
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Genomic context

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See CAPN11 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
23
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (30010363..30023242, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (29937856..29952294, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 29 member 1 Neighboring gene spectrin beta chain, brain 4-like Neighboring gene transmembrane protein 63B Neighboring gene microRNA 4732 Neighboring gene mitochondrial ribosomal protein L14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Study on association of single nucleotide polymorphism of CAPN1 gene with muscle fibre and carcass traits in quality chicken populations. Zhang ZR, et al. J Anim Breed Genet, 2008 Aug. PMID 18727211
  2. [Study on correlation between single nucleotide polymorphism of CAPN1 gene and muscle tenderness and carcass traits in chicken]. Zhang ZR, et al. Yi Chuan, 2007 Aug. PMID 17681928
  3. Evolutionary origin of a calcium-dependent protease by fusion of genes for a thiol protease and a calcium-binding protein? Ohno S, et al. Nature, 1984 Dec 6-12. PMID 6095110
  4. Gene structure of calcium-dependent protease retains the ancestral organization of the calcium-binding protein gene. Emori Y, et al. FEBS Lett, 1986 Jan 6. PMID 3000828
  5. A newly classified vertebrate calpain protease, directly ancestral to CAPN1 and 2, episodically evolved a restricted physiological function in placental mammals. Macqueen DJ, et al. Mol Biol Evol, 2010 Aug. PMID 20223856

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Results showed that CAPN1 gene may be the major gene affecting the tenderness traits of chicken or it links with the major gene, and the the polymorphic site may be used as molecular markers for meat tenderness and chicken quality.
    Title: [Study on correlation between single nucleotide polymorphism of CAPN1 gene and muscle tenderness and carcass traits in chicken].
  2. The CAPN1 gene has been associated with meat quality traits in chicken.
    Title: Study on association of single nucleotide polymorphism of CAPN1 gene with muscle fibre and carcass traits in quality chicken populations.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-1 catalytic subunit
Names
calcium-activated neutral proteinase
calpain-1 large subunit
mu/M-type
NP_990634.1
XP_015139111.1
XP_040552800.1
XP_040552801.1
XP_046769182.1
XP_046769183.1
XP_046769184.1
XP_046769185.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205303.1 → NP_990634.1  calpain-1 catalytic subunit

    See identical proteins and their annotated locations for NP_990634.1

    Status: PROVISIONAL

    Source sequence(s)
    X01415
    UniProtKB/Swiss-Prot
    P00789
    UniProtKB/TrEMBL
    A4ZZ65
    Conserved Domains (3) summary
    cd00214
    Location:358 → 515
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd16198
    Location:537 → 705
    EFh_PEF_CAPN1; Penta-EF hand, calcium binding motifs, found in mu-type calpain (CAPN1)
    pfam00648
    Location:49 → 345
    Peptidase_C2; Calpain family cysteine protease

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    30010363..30023242 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040696866.2 → XP_040552800.1  calpain-1 catalytic subunit isoform X1

    UniProtKB/Swiss-Prot
    P00789
    UniProtKB/TrEMBL
    A4ZZ65
    Conserved Domains (3) summary
    cd00214
    Location:358 → 515
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd16198
    Location:537 → 705
    EFh_PEF_CAPN1; Penta-EF hand, calcium binding motifs, found in mu-type calpain (CAPN1)
    pfam00648
    Location:49 → 345
    Peptidase_C2; Calpain family cysteine protease

  2. XM_015283625.4 → XP_015139111.1  calpain-1 catalytic subunit isoform X1

    UniProtKB/Swiss-Prot
    P00789
    UniProtKB/TrEMBL
    A4ZZ65
    Related
    ENSGALP00010028077.1, ENSGALT00010047386.1
    Conserved Domains (3) summary
    cd00214
    Location:358 → 515
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd16198
    Location:537 → 705
    EFh_PEF_CAPN1; Penta-EF hand, calcium binding motifs, found in mu-type calpain (CAPN1)
    pfam00648
    Location:49 → 345
    Peptidase_C2; Calpain family cysteine protease

  3. XM_040696867.2 → XP_040552801.1  calpain-1 catalytic subunit isoform X1

    UniProtKB/Swiss-Prot
    P00789
    UniProtKB/TrEMBL
    A4ZZ65
    Conserved Domains (3) summary
    cd00214
    Location:358 → 515
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd16198
    Location:537 → 705
    EFh_PEF_CAPN1; Penta-EF hand, calcium binding motifs, found in mu-type calpain (CAPN1)
    pfam00648
    Location:49 → 345
    Peptidase_C2; Calpain family cysteine protease

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    29937856..29952294 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046913227.1 → XP_046769183.1  calpain-1 catalytic subunit isoform X1

    UniProtKB/Swiss-Prot
    P00789

  2. XM_046913226.1 → XP_046769182.1  calpain-1 catalytic subunit isoform X1

    UniProtKB/Swiss-Prot
    P00789

  3. XM_046913229.1 → XP_046769185.1  calpain-1 catalytic subunit isoform X1

    UniProtKB/Swiss-Prot
    P00789

  4. XM_046913228.1 → XP_046769184.1  calpain-1 catalytic subunit isoform X1

    UniProtKB/Swiss-Prot
    P00789
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P00789.2 GenPept UniProtKB/Swiss-Prot:P00789

Gene LinkOut

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