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CEBPB CCAAT/enhancer binding protein beta [ Gallus gallus (chicken) ]

Gene ID: 396185, updated on 5-Mar-2024

Summary

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Symbol
CEBPBprovided by CGNC
Full Name
CCAAT/enhancer binding protein betaprovided by CGNC
Primary source
CGNC:6065
See related
Ensembl:ENSGALG00010014573
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
NF-M
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
1
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 20 NC_052551.1 (14051150..14052880, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 20 NC_052592.1 (13837070..13838801, complement)

Chromosome 20 - NC_052551.1Genomic Context describing neighboring genes Neighboring gene par-6 family cell polarity regulator beta Neighboring gene family with sequence similarity 65 member C Neighboring gene protein tyrosine phosphatase non-receptor type 1 Neighboring gene uncharacterized LOC124417326 Neighboring gene uncharacterized LOC121107307 Neighboring gene transmembrane protein 189

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300. Steinmann S, et al. Oncogene, 2009 Jul 2. PMID 19448669
  2. Regulation of C/EBPbeta mRNA expression and C/EBPbeta promoter activity by protein kinases A and C in a myelomonocytic cell line (HD11). Goethe R, et al. Inflamm Res, 2007 Jul. PMID 17659432
  3. Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors. Burk O, et al. EMBO J, 1993 May. PMID 8491193, Free PMC Article
  4. The NF-M transcription factor is related to C/EBP beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells. Katz S, et al. EMBO J, 1993 Apr. PMID 8467792, Free PMC Article
  5. Identification of a Myb-responsive enhancer of the chicken C/EBPbeta gene. Kintscher J, et al. Oncogene, 2004 Jul 29. PMID 15195136

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. C-EBP beta involved in lipid metabolism in Beijing-You chickens.
    Title: Expression profiles of key transcription factors involved in lipid metabolism in Beijing-You chickens.
  2. modulation of the C/EBPbeta-induced phosphorylation of p300 is a new mechanism of transcriptional suppression by v-Myc.
    Title: v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300.
  3. In the absence of Myb, C/EBPbeta triggers the initial steps of chromatin opening at the mim-1 enhancer without inducing transcription of the gene.
    Title: C/EBPbeta induces chromatin opening at a cell-type-specific enhancer.
  4. Results indicate that the C/EBPbeta gene is regulated transcriptionally as well as post-transcriptionally in response to forskolin and PMA, and the forskolin responsiveness of the C/EBPbeta promoter seems to depend on cellular cAMP turnover.
    Title: Regulation of C/EBPbeta mRNA expression and C/EBPbeta promoter activity by protein kinases A and C in a myelomonocytic cell line (HD11).
  5. Myb activation of the promoter requires the cooperation with C/EBPbeta, activation of the enhancer by Myb is independent of CCAAT box/enhancer binding protein beta
    Title: Identification of a Myb-responsive enhancer of the chicken C/EBPbeta gene.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CCAAT/enhancer-binding protein beta
Names
CCAAT box/enhancer binding protein beta
CCAAT/enhancer binding protein (C/EBP), beta
CCR protein
c/EBP beta
transcription factor NF-M

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205253.3 → NP_990584.1  CCAAT/enhancer-binding protein beta

    See identical proteins and their annotated locations for NP_990584.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000328
    UniProtKB/Swiss-Prot
    Q05826, Q540C6
    Related
    ENSGALP00010020452.1, ENSGALT00010034993.1
    Conserved Domains (1) summary
    cd14712
    Location:247 → 317
    bZIP_CEBPB; Basic leucine zipper (bZIP) domain of CCAAT/enhancer-binding protein beta (CEBPB): a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052551.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    14051150..14052880 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052592.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    13837070..13838801 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q05826.1 GenPept UniProtKB/Swiss-Prot:Q05826

Gene LinkOut

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