RBP4 retinol binding protein 4 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: RBP4provided by CGNC
Official Full Name: retinol binding protein 4provided by CGNC
Primary source: CGNC:49812
See related: Ensembl:ENSGALG00010020357
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: RBP; RBP4A
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 6

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	6	NC_052537.1 (21185245..21192899)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	6	NC_052578.1 (21076587..21084246)

Chromosome 6 - NC_052537.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Excessive vitamin E could increase the concentration of vitamin A in liver by inhibiting retinol binding protein synthesis in hepatocytes.
Title: High levels of vitamin E affect retinol binding protein but not CYP26A1 in liver and hepatocytes from laying hens.
In the absence of retinol, the constitutive secretion of chicken plasma RBP is higher than the human plasma retinol-binding protein.
Title: Role of the C-termini of human and chicken plasma retinol-binding proteins.
RBP4 is not synthesized by the ovarian follicles of chicken.
Title: Retinol in avian oogenesis: molecular properties of the carrier protein.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables retinol binding	IEA Inferred from Electronic Annotation more info	PubMed
enables retinol transmembrane transporter activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in retinol transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: retinol-binding protein 4

Names: PRBP; plasma retinol-binding protein; retinol binding protein 4 A, plasma; retinol binding protein 4, plasma

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205238.2 → NP_990569.1 retinol-binding protein 4 precursor

See identical proteins and their annotated locations for NP_990569.1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000232

UniProtKB/Swiss-Prot

P41263

UniProtKB/TrEMBL

A0A8V0ZE04

Related

ENSGALP00010029086.1, ENSGALT00010049196.1

Conserved Domains (1) summary

pfam00061
Location:42 → 179

Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

21185245..21192899

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_025151488.3 → XP_025007256.1 retinol-binding protein 4 isoform X1

UniProtKB/TrEMBL

A0A8V0Z756, A0A8V0ZCY7

Related

ENSGALP00010029075.1, ENSGALT00010049178.1

Conserved Domains (1) summary

pfam00061
Location:46 → 183

Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family