NFKBIA NFKB inhibitor alpha [Gallus gallus (chicken)] - Gene

Summary

Symbol: NFKBIAprovided by CGNC
Full Name: NFKB inhibitor alphaprovided by CGNC
Primary source: CGNC:66220
See related: Ensembl:ENSGALG00010005913
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	5	NC_052536.1 (35701640..35705164, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	5	NC_052577.1 (35672082..35675600, complement)

Chromosome 5 - NC_052536.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MiR-196-5p involvement in selenium deficiency-induced immune damage via targeting of NFkappaBIA in the chicken trachea.
Title: MiR-196-5p involvement in selenium deficiency-induced immune damage via targeting of NFκBIA in the chicken trachea.
RNA sequencing results revealed that the chicken NFKBIA was differently expressed between the intestinal mucosal layer of Necrotic enteritis induced chicken lines that are resistant and sensitive to avian leukosis and Marek's disease.
Title: Expression analysis of cytosolic DNA-sensing pathway genes in the intestinal mucosal layer of necrotic enteritis-induced chicken.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: NF-kappa-B inhibitor alpha

Names: I kappa B-alpha; IKB-alpha; NF-kappaB inhibitor alpha; REL-associated protein pp40; Rel-associated pp40; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001001472.3 → NP_001001472.3 NF-kappa-B inhibitor alpha

Status: VALIDATED

Source sequence(s)

JAENSK010000215

UniProtKB/Swiss-Prot

Q91974

Related

ENSGALP00010008340.1, ENSGALT00010014168.1

Conserved Domains (2) summary

COG0666
Location:40 → 244

ANKYR; Ankyrin repeat [Signal transduction mechanisms]

sd00045
Location:147 → 184

ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

35701640..35705164 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

35672082..35675600 complement

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GenBank, FASTA, Sequence Viewer (Graphics)